St Louis Cardinals vs Milwaukee Brewers Prediction, Preview and Odds - 06/14/2025

Game Time: 4:10 pm ET, Saturday, June 14, 2025

Venue:  American Family Field, Milwaukee, WI

Where to Watch:  Fox Sports 1

DraftKings:  Moneyline odds:  Cardinals +104, Brewers -126; Over/Under:  8 runs

Bet365:  Moneyline odds:  Cardinals +105, Brewers -125; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Cardinals +105, Brewers -125; Over/Under:  8 runs

St Louis Cardinals:  36-33 (3rd place, NL Central)

Milwaukee Brewers:  37-33 (2nd place, NL Central)

Do not miss out on our expert handicapper analysis! Matt Fargo is on a HOT STREAK in the MLB on a 28-29 MLB RUN for +$6,210 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

St Louis Cardinals:  3-7 last 10

Milwaukee Brewers:  5-5 last 10

The Cardinals are entering this series off a loss and got swept in their 3-game series against the Toronto Blue Jays 3-0 in their last series. They enter this game with a 36-33 record overall and have a road record of 14-19. This is the 3rd game of a 4-game series with the Brewers on Saturday with the 2nd game still to be played on Friday. The Cardinals lost the series opener of this series on Thursday. Their offense ranks 11th in the MLB with a .718 OPS. Erick Fedde is their starting pitcher on Friday while Andre Pallante is making his start in this game on Saturday. He is 4-3 with a 4.75 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 ER, 0 HR, and 1 BB with 3 Ks on 7 hits through 6 IP against the Toronto Blue Jays.

The Brewers are entering this series off a loss and lost their 3-game series against the Atlanta Braves 2-1 in their last series. They enter this game with a 37-33 record overall and have a home record of 21-14. This is the 3rd game of a 4-game series with the Cardinals on Saturday with the 2nd game of this series still to be played on Friday. The Brewers won the 1st game of this series on Thursday. Their offense ranks 25th in the MLB with a .676 OPS. Freddy Peralta is their starting pitcher on Friday while Jose Quintana is making his start in this game on Saturday. He is 4-1 with a 2.66 ERA this season. His team won their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 1 earned run, 0 homers, and 3 walks with 4 strikeouts on 5 hits through 5 innings pitched against the San Diego Padres.

The current betting odds have the Brewers listed as a slight favorite in this game according to Draftkings Sportsbook. The Cardinals have looked good in their games this season with their 36-33 record overall which has them right near the top of the NL Central. They haven't been a great road team though with their 14-19 road record. Meanwhile, the Brewers have looked good in their games this season with their 37-33 record overall which has them right in the middle of the NL Central. They have looked a lot better in their own ballpark this year with their 21-14 home record too. The Brewers haven't been at their best lately, but they have still looked a lot better than the Cardinals who just got swept by the Blue Jays in their last series and is now 3-7 in their last 10 games. Pallante is on the mound for the Cardinals in this one and he hasn't looked great this season. He is 4-3 with a 4.75 ERA and has been really up and down all season. He hasn't been at his best lately either, only giving up 2 earned runs in his last start but his team still losing their last 2 games with him starting. The Brewers have been the opposite lately as they are going with Quintana in this one and the team has won 2 games in a row with him on the mound. He has also looked great this season as he is 4-1 with a 2.66 ERA and coming off another good start in which he gave up 1 earned run, something that has been a common theme for him this year. The Brewers have also looked a lot better at home this year and they can take advantage of a bad road team in the Cardinals. The best way to place a bet here is on the Brewers to win this game. 

Cardinals Brewers Prediction:  Our MLB Pick for Saturday, June 14, 2025 (4:10 pm ET start time) is Brewers 6 Cardinals 2.

Don't miss our champion handicappers free picks, best bets, and expert baseball picks today.  And if you enjoyed this St Louis Cardinals Milwaukee Brewers prediction, be sure to drop by every day for our daily MLB projections and previews.

St Louis Cardinals: 189-203 (-26.3 units) on the moneyline in all games. 55-63 (-17.1 units) on the moneyline against division opponents. 53-57 (-9.9 units) on the moneyline against left-handed starters. 31-22 UNDER vs. an NL starting pitcher whose ERA is 3.20 or better.

Milwaukee Brewers: 222-176 (+27.2 units) on the moneyline in all games. 117-84 (+8.3 units) on the moneyline in home games. 161-116 (+35.7 units) on the moneyline against right-handed starters. 20-6 UNDER when playing against a team  with a winning record.

St Louis Cardinals:  B. Donovan (2B) Day To Day - Toe. J. Walker (RF) Ten Day IL - Wrist. Z. Thompson (RP) Sixty Day IL - Lat.

Milwaukee Brewers:  J. Misiorowski (SP) Day To Day - Calf/Quad. N. Cortes (SP) Sixty Day IL - Elbow. C. Thomas (SP) Sixty Day IL - Elbow. B. Woodruff (SP) Sixty Day IL - Shoulder. G. Mitchell (CF) Ten Day IL - Oblique. B. Perkins (CF) Sixty Day IL - Shin. R. Gasser (SP) Sixty Day IL - Elbow.

“Even in the first four [innings], I didn’t feel great, and I felt like I was just getting by. Then, the fifth [inning] happened.” - Sonny Gray after their loss against the Brewers in their game on Thursday.

“I’ve been playing this day out in my head forever. I thought I was going to give up a few hits, get your welcome to The Show. But I kind of rolled with it, and now we’re here.” - Jacob Misiorowski after their win against the Cardinals in his MLB debut on Thursday.

Lars Nootbaar (L) LF

Masyn Winn (R) SS

Iván Herrera (R) DH

Willson Contreras (R) 1B

Alec Burleson (L) RF

Nolan Arenado (R) 3B

Nolan Gorman (L) 2B

Pedro Pagés (R) C

Victor Scott II (L) CF

Sal Frelick (L) RF

Jackson Chourio (R) CF

William Contreras (R) C

Christian Yelich (L) DH

Rhys Hoskins (R) 1B

Isaac Collins (S) LF

Brice Turang (L) 2B

Caleb Durbin (R) 3B

Joey Ortiz (R) SS

Batting Average:  Thomas Saggese (.341)

Hits:  Brendan Donovan (77)

Home Runs:  Lars Nootbaar (8)

RBI:  Willson Contreras (43)

Stolen Bases:  Victor Scott (18)

Wins:  Sonny Gray (7)

Saves:  Ryan Helsley (13)

ERA:  Andre Granillo (0.00)

Batting Average:  Sal Frelick (.292)

Hits:  Jackson Chourio (76)

Home Runs:  Christian Yelich (13)

RBI:  Christian Yelich (41)

Stolen Bases:  Brice Turang (15)

Wins:  Freddy Peralta (5)

Saves:  Trevor Megill (13)

ERA:  Aaron Ashby (0.00)

Managers:

St Louis Cardinals: Oliver Marmol (4th season)

Milwaukee Brewers: Pat Murphy (2nd season)