St Louis Cardinals vs Milwaukee Brewers Prediction, Preview and Odds - 06/13/2025

Game Time: 8:10 pm ET, Friday, June 13, 2025

Venue:  American Family Field, Milwaukee, WI

Where to Watch:  FDSWI

DraftKings:  Moneyline odds:  Cardinals +128, Brewers -157; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Cardinals +130, Brewers -155; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Cardinals +130, Brewers -155; Over/Under:  7.5 runs

St Louis Cardinals:  36-32 (2nd place, NL Central)

Milwaukee Brewers:  36-33 (3rd place, NL Central)

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St Louis Cardinals:  3-7 last 10

Milwaukee Brewers:  5-5 last 10

The Cardinals are entering this series off a loss and got swept in their 3-game series against the Toronto Blue Jays 3-0 in their last series. They enter this game with a 36-32 record overall and have a road record of 14-18. This is the 2nd game of a 4-game series with the Brewers on Friday with the series opener still to be played on Thursday. Their offense ranks 11th in the MLB with a .722 OPS. Sonny Gray is their starting pitcher on Thursday while Erick Fedde is making his start in this game on Friday. He is 3-5 with a 3.54 ERA this season. His team lost 4 of their last 5 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 ER, 0 HR, and 4 BB with 2 Ks on 4 hits through 5.1 IP against the Los Angeles Dodgers.

The Brewers are entering this series off a loss and lost their 3-game series against the Atlanta Braves 2-1 in their last series. They enter this game with a 36-33 record overall and have a home record of 20-14. This is the 2nd game of a 4-game series with the Cardinals on Friday with the 1st game of this series still to be played on Thursday. Their offense ranks 26th in the MLB with a .674 OPS. Rookie pitcher Jacob Misiorowski is their starting pitcher on Thursday while Freddy Peralta is making his start in this game on Friday. He is 5-4 with a 2.69 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 2 walks with 3 strikeouts on 1 hit through 6 innings pitched against the San Diego Padres.

The current betting odds have the Brewers listed as a favorite in this game according to Draftkings Sportsbook. The Cardinals have looked good in their games this season with their 36-32 record overall which has them right near the top of the NL Central. They haven't been a great road team though with their 14-18 road record. Meanwhile, the Brewers have looked good in their games this season with their 36-33 record overall which has them right in the middle of the NL Central. They have looked a lot better in their own ballpark this year with their 20-14 home record too. The Brewers are coming off a series loss to the Braves, but the Cardinals just got swept by the Blue Jays and they are also 3-7 in their last 10 games as they have been slumping lately. Fedde is on the mound for the Cardinals in this one but he hasn't been great for them lately. He is 3-5 with a 3.54 ERA this season and he is coming off a great start in which he gave up no runs, but that hasn't been a common theme for him this year. He won't have back-to-back starts like that and the team hasn't even had much success with him lately either, losing 4 of their last 5 games with him starting. Peralta is on the mound for the Brewers and he has been one of their better starters this year. He is 5-4 with a 2.69 ERA and hasn't been giving up many runs in any of his starts. He is coming off a start in which he gave up no runs which has been a common theme for him this year, and the team will be looking to get him a win here since they have lost 2 games in a row with him starting even though he has been great in those. The best way to place a bet here is on the Brewers to win this game. 

Cardinals Brewers Prediction:  Our MLB Pick for Friday, June 13, 2025 (8:10 pm ET start time) is Brewers 4 Cardinals 1.

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St Louis Cardinals: 189-202 (-25.1 units) on the moneyline in all games. 55-62 (-15.9 units) on the moneyline against division opponents. 136-145 (-15.2 units) on the moneyline against right-handed starters. 40-27 OVER vs. poor power teams - averaging 0.9 or less HR's/game.

Milwaukee Brewers: 221-176 (+26.1 units) on the moneyline in all games. 116-84 (+7.3 units) on the moneyline in home games. 160-116 (+34.6 units) on the moneyline against right-handed starters. 17-9 OVER at home vs. a starting pitcher who gives up 0.5 or less HR's/start.

St Louis Cardinals:  B. Donovan (2B) Day To Day - Toe. J. Walker (RF) Ten Day IL - Wrist. Z. Thompson (RP) Sixty Day IL - Lat.

Milwaukee Brewers:  C. Yelich (LF) Day To Day - Wrist. N. Cortes (SP) Sixty Day IL - Elbow. C. Thomas (SP) Sixty Day IL - Elbow. B. Woodruff (SP) Fifteen Day IL - Shoulder. G. Mitchell (CF) Ten Day IL - Oblique. B. Perkins (CF) Sixty Day IL - Shin. R. Gasser (SP) Sixty Day IL - Elbow.

“It was still [about] average velo over the course of the entire outing. It was still better than last time. He felt much better, so that's a plus. So, him coming out of this outing feeling positive ... just physically getting through that outing, we're in a good spot.” - Oliver Marmol after his team’s loss against the Blue Jays in their game on Wednesday.

“It’s just more precautionary. He did not swing [Tuesday], but made himself available to pinch-run or whatever we needed. Today he’s going to test it and swing a little bit. We hope we can avoid imaging or anything else, that he feels good enough that the swelling is out of there and he can progress. You guys know, baseball players, when you deal with something in the wrist or the hand, they’re delicate. We just hope there’s nothing worse in there.” - Pat Murphy on the injury to Christian Yelich after his team’s loss against the Braves in their game on Wednesday.

Lars Nootbaar (L) LF

Masyn Winn (R) SS

Iván Herrera (R) DH

Willson Contreras (R) 1B

Alec Burleson (L) RF

Nolan Arenado (R) 3B

Nolan Gorman (L) 2B

Yohel Pozo (R) C

Victor Scott II (L) CF

Brice Turang (L) 2B

Jackson Chourio (R) CF

William Contreras (R) DH

Jake Bauers (L) LF

Rhys Hoskins (R) 1B

Sal Frelick (L) RF

Caleb Durbin (R) 3B

Joey Ortiz (R) SS

Eric Haase (R) C

Batting Average:  Thomas Saggese (.341)

Hits:  Brendan Donovan (77)

Home Runs:  Lars Nootbaar (8)

RBI:  Willson Contreras (43)

Stolen Bases:  Victor Scott (18)

Wins:  Sonny Gray (7)

Saves:  Ryan Helsley (13)

ERA:  Phil Maton (2.16)

Batting Average:  Sal Frelick (.284)

Hits:  Jackson Chourio (75)

Home Runs:  Christian Yelich (13)

RBI:  Christian Yelich (41)

Stolen Bases:  Brice Turang (15)

Wins:  Freddy Peralta (5)

Saves:  Trevor Megill (13)

ERA:  Aaron Ashby (0.00)

Managers:

St Louis Cardinals: Oliver Marmol (4th season)

Milwaukee Brewers: Pat Murphy (2nd season)