Minnesota Twins vs Cincinnati Reds Prediction, Preview and Odds - 06/19/2025

Game Time: 12:40 pm ET, Thursday, June 19, 2025

Venue:  Great American Ball Park, Cincinnati, OH

Where to Watch:  FDSOH

DraftKings:  Moneyline odds:  Twins -108, Reds -112; Over/Under:  9 runs

Bet365:  Moneyline odds:  Twins -110, Reds -110; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Twins -110, Reds -110; Over/Under:  9 runs

Minnesota Twins:  36-36 (3rd place, AL Central)

Cincinnati Reds:  38-35 (4th place, NL Central)

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Minnesota Twins:  2-8 last 10

Cincinnati Reds:  8-2 last 10

The Twins are entering this series off a loss and got swept in their 3-game series against the Houston Astros 3-0 in their last series. They enter this game with a 36-36 record overall and have a road record of 16-24. This is the series finale of a 3-game series with the Reds on Thursday with the 2nd game still to be played on Wednesday. The Twins lost the series opener of this series on Tuesday. Their offense ranks 18th in the MLB with a .701 OPS. Bailey Ober is their starting pitcher on Wednesday while Chris Paddack is making his start in this game on Thursday. He is 2-6 with a 4.30 ERA this season. His team lost their last 5 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 8 ER, 1 HR, and 1 BB with 1 SO on 12 hits through 4 IP against the Houston Astros.

The Reds are entering this series off a win and won their 3-game series against the Detroit Tigers 2-1 in their last series. They enter this game with a 38-35 record overall and have a home record of 19-16. This is the 3rd game of a 3-game series with the Twins on Thursday with the 2nd game of this series still to be played on Wednesday. The Reds won the 1st game of this series on Tuesday. Their offense ranks 10th in the MLB with a .725 OPS. Nick Lodolo is their starting pitcher on Wednesday while Nick Martinez is making his start in this game on Thursday. He is 4-7 with a 3.92 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 earned runs, 3 homers, and 2 walks with 5 strikeouts on 8 hits through 5 innings pitched against the Detroit Tigers.

The current betting odds have the Reds listed as a slight favorite in this game according to Draftkings Sportsbook. The Reds have looked good in their games this season with their 38-35 record overall, but that record has them right near the bottom of the NL Central in a competitive division. They have looked better in their own ballpark though with their 19-16 home record this year. Meanwhile, the Twins have looked good in their games this season with their 36-36 record overall which has them right near the top of the AL Central, but that record doesn't really have them near the division leaders. They haven't been a good road team this year either with their 16-24 road record. They haven't looked good in their games lately as they are 2-8 in their last 10 games while the Reds have been red hot lately, going 8-2 in their last 10. Martinez is on the mound for the Reds in this one and he hasn't looked great this year, but he should pitch better in this home game and give the Reds the edge here. He is 4-7 with a 3.92 ERA and he gave up 4 earned runs in his last start. The team has also lost 2 of the last 3 games he started in, but their offense has looked a lot better lately and that will give them the edge since Paddack is on the mound for the Twins. Paddack is 2-6 with a 4.30 ERA this season and he has been giving up a lot of runs all year. He is coming off a terrible start in which he gave up 8 earned runs and the team has had no success with him lately either, losing 5 games in a row with him starting. The Reds have the better offense right now and have looked a lot better as a team lately. The best way to place a bet here is on the Reds to win this game. 

Twins Reds Prediction:  Our MLB Pick for Thursday, June 19, 2025 (12:40 pm ET start time) is Reds 6 Twins 4.

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Minnesota Twins: 17-22 (-11.3 units) on the moneyline against NL Central opponents. 207-194 (-32 units) on the moneyline in all games. 95-108 (-20.8 units) on the moneyline in road games. 61-37 UNDER as an underdog of +100 to +150.

Cincinnati Reds: 195-200 (+9.4 units) on the moneyline in all games. 64-55 (+15.6 units) on the moneyline in an inter-league game. 60-53 (+13.1 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 15-5 UNDER at home against AL Central opponents.

Minnesota Twins:  R. Jeffers (C) Day To Day - Arm. R. Lewis (3B) Ten Day IL - Hamstring. P. Lopez (SP) Sixty Day IL - Shoulder. Z. Matthews (SP) Fifteen Day IL - Shoulder. L. Keaschall (2B) Sixty Day IL - Forearm.

Cincinnati Reds:  G. Ashcraft (RP) Fifteen Day IL - Groin. H. Greene (SP) Fifteen Day IL - Groin. R. Lowder (SP) Sixty Day IL - Forearm. A. Hays (LF) Ten Day IL - Foot. C. Spiers (RP) Sixty Day IL - Shoulder. T. Callihan (LF) Sixty Day IL - Forearm. N. Marte (3B) Ten Day IL - Side. J. Candelario (3B) Ten Day IL - Back. B. Williamson (SP) Sixty Day IL - Elbow. J. Aguiar (SP) Sixty Day IL - Elbow.

“It's a very winnable game for us, and we know it. Probably a few things we could have done during the game to help ourselves and help our cause. Truthfully, it's a game where we can focus more looking at ourselves and the fundamentals of the game.” - Rocco Baldelli after his team’s loss against the Reds in their game on Tuesday.

“It was like when they say the same things that make you laugh make you cry. We get four after [the Twins] think they get the third out, and they do the same exact thing to us. We made some mistakes, but we did some really good things.” - Terry Francona after his team’s win against the Twins in their game on Tuesday.

Byron Buxton (R) CF

Ryan Jeffers (R) C

Willi Castro (S) RF

Carlos Correa (R) SS

Ty France (R) 1B

Brooks Lee (S) 2B

Trevor Larnach (L) DH

Harrison Bader (R) LF

Jonah Bride (R) 3B

TJ Friedl (L) CF

Gavin Lux (L) DH

Elly De La Cruz (S) SS

Tyler Stephenson (R) C

Christian Encarnacion-Strand (R) 3B

Will Benson (L) LF

Spencer Steer (R) 1B

Jake Fraley (L) RF

Matt McLain (R) 2B

Batting Average:  Luke Keaschall (.368)

Hits:  Ty France (68)

Home Runs:  Byron Buxton (12)

RBI:  Byron Buxton (42)

Stolen Bases:  Byron Buxton (12)

Wins:  Joe Ryan (7)

Saves:  Jhoan Duran (10)

ERA:  Danny Coulombe (0.48)

Batting Average:  Austin Wynns (.400)

Hits:  TJ Friedl (76)

Home Runs:  Elly De La Cruz (16)

RBI:  Elly De La Cruz (50)

Stolen Bases:  Elly De La Cruz (21)

Wins:  Brady Singer (7)

Saves:  Emilio Pagán (17)

ERA:  Lyon Richardson (1.37)

Managers:

Minnesota Twins: Rocco Baldelli (7th season)

Cincinnati Reds: Terry Francona (1st season)