Minnesota Twins vs Cincinnati Reds Prediction, Preview and Odds - 06/17/2025

Game Time: 7:10 pm ET, Tuesday, June 17, 2025

Venue:  Great American Ball Park, Cincinnati, OH

Where to Watch:  WXIX, FDSOH

DraftKings:  Moneyline odds:  Twins -105, Reds -115; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Twins -105, Reds -115; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Twins -105, Reds -115; Over/Under:  8.5 runs

Minnesota Twins:  36-35 (2nd place, AL Central)

Cincinnati Reds:  37-35 (4th place, NL Central)

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Minnesota Twins:  2-8 last 10

Cincinnati Reds:  7-3 last 10

The Twins are entering this series off a loss and got swept in their 3-game series against the Houston Astros 3-0 in their last series. They enter this game with a 36-35 record overall and have a road record of 16-23. This is the series opener of a 3-game series with the Reds on Tuesday and they have Monday off as a day of rest. Their offense ranks 18th in the MLB with a .700 OPS. Simeon Woods Richardson was their starting pitcher on Sunday while David Festa is making his start in this game on Tuesday. He is 1-1 with a 4.76 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 ER, 1 HR, and 2 BB with 4 SO on 3 hits through 6 IP against the Texas Rangers.

The Reds are entering this series off a win and won their 3-game series against the Detroit Tigers 2-1 in their last series. They enter this game with a 37-35 record overall and have a home record of 18-16. This is the 1st game of a 3-game series with the Twins on Tuesday and they have Monday off as a day of rest. Their offense ranks 10th in the MLB with a .727 OPS. Wade Miley was their starting pitcher on Sunday while Andrew Abbott is making his start in this game on Tuesday. He is 6-1 with a 1.87 ERA this season. His team won 4 of their last 5 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 1 walk with 5 strikeouts on 3 hits through 9 innings pitched against the Cleveland Guardians.

The current betting odds have the Reds listed as a slight favorite in this game according to Draftkings Sportsbook. The Reds have looked good in their games this season with their 37-35 record overall, but that record has them right near the bottom of the NL Central in a competitive division. They have looked better in their own ballpark though with their 18-16 home record this year. Meanwhile, the Twins have looked good in their games this season with their 36-35 record overall which has them right near the top of the AL Central, but that record doesn't really have them near the division leaders. They haven't been a good road team this year either with their 16-23 road record. The Twins just got swept by the Astros in their last series and they have looked terrible lately as they are 2-8 in their last 10 games while the Reds are 7-3 in their last 10 and have been getting hot. The Reds are also going to have their ace on the mound in this one. Abbott is starting and he is 6-1 with a 1.87 ERA. He gave up no runs in his last start and that has been a common theme for him this year. His team has also won 4 of their last 5 games with him starting and he will have another good game against this ice cold Twins team. Festa is on the mound for the Twins and he hasn't looked great this season. He is 1-1 with a 4.76 ERA and he has been giving up quite a few runs this year. He only gave up 2 earned runs in his last start and the team has had some success with him lately too, but he will get himself into trouble against this hot lineup while the Twins struggle to offer him run support. The best way to place a bet here is on the Reds to win this game. 

Twins Reds Prediction:  Our MLB Pick for Tuesday, June 17, 2025 (7:10 pm ET start time) is Reds 4 Twins 1.

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Minnesota Twins: 17-21 (-10.3 units) on the moneyline against NL Central opponents. 207-193 (-31 units) on the moneyline in all games. 95-107 (-19.8 units) on the moneyline in road games. 18-7 UNDER on the road when the money line is +125 to -125.

Cincinnati Reds: 194-200 (+8.4 units) on the moneyline in all games. 63-55 (+14.6 units) on the moneyline in an inter-league game. 59-53 (+12.1 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 18-9 UNDER when the money line is -100 to -150.

Minnesota Twins:  B. Buxton (CF) Day To Day - Elbow. R. Lewis (3B) Ten Day IL - Hamstring. P. Lopez (SP) Sixty Day IL - Shoulder. Z. Matthews (SP) Fifteen Day IL - Shoulder. L. Keaschall (2B) Sixty Day IL - Forearm.

Cincinnati Reds:  H. Greene (SP) Fifteen Day IL - Groin. R. Lowder (SP) Sixty Day IL - Forearm. A. Hays (LF) Ten Day IL - Foot. C. Spiers (RP) Sixty Day IL - Shoulder. T. Callihan (LF) Sixty Day IL - Forearm. N. Marte (3B) Ten Day IL - Side. J. Candelario (3B) Ten Day IL - Back. B. Williamson (SP) Sixty Day IL - Elbow. J. Aguiar (SP) Sixty Day IL - Elbow.

“I think he’s doing a good job of hunting some pitches and being prepared going into his at-bats. And we’ve talked about him last year compared to this year. He’s grown a lot and continues to get better. Every week you kind of see him doing different things out there on the field. He’s not just going up there looking for the ball -- see it, hit it and attacking everything. He’s actually going up there with a good plan. Again, an improving player and a guy with good ability, and it’s exciting to watch a young guy make those improvements.” - Rocco Baldelli after his team’s loss against the Astros in their game on Sunday.

“If he’s 90 percent running, he’s out. We’ve talked to them all of the time. You can’t pick your spots when you’re going to hustle. When you do [hustle], you’ve got a chance to win a game because of it.” - Terry Francona after his team’s win against the Tigers in their game on Sunday.

Ryan Jeffers (R) DH

Carlos Correa (R) SS

Willi Castro (S) LF

Ty France (R) 1B

Matt Wallner (L) RF

Jonah Bride (R) 3B

Harrison Bader (R) CF

Brooks Lee (S) 2B

Christian Vázquez (R) C

TJ Friedl (L) CF

Matt McLain (R) SS

Elly De La Cruz (S) DH

Tyler Stephenson (R) C

Christian Encarnacion-Strand (R) 1B

Connor Joe (R) LF

Gavin Lux (L) 2B

Santiago Espinal (R) 3B

Jake Fraley (L) RF

Batting Average:  Luke Keaschall (.368)

Hits:  Ty France (68)

Home Runs:  Byron Buxton (11)

RBI:  Byron Buxton (41)

Stolen Bases:  Byron Buxton (12)

Wins:  Joe Ryan (7)

Saves:  Jhoan Duran (10)

ERA:  Danny Coulombe (0.49)

Batting Average:  Austin Wynns (.400)

Hits:  Elly De La Cruz (75)

Home Runs:  Elly De La Cruz (16)

RBI:  Elly De La Cruz (50)

Stolen Bases:  Elly De La Cruz (20)

Wins:  Brady Singer (7)

Saves:  Emilio Pagán (16)

ERA:  Lyon Richardson (1.37)

Managers:

Minnesota Twins: Rocco Baldelli (7th season)

Cincinnati Reds: Terry Francona (1st season)