Milwaukee Brewers vs Minnesota Twins Prediction, Preview and Odds - 06/20/2025

Game Time: 8:10 pm ET, Friday, June 20, 2025

Venue:  Target Field, Minneapolis, MN

Where to Watch:  TWINS.tv

DraftKings:  Moneyline odds:  Brewers +138, Twins -169; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Brewers +140, Twins -170; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Brewers +140, Twins -165; Over/Under:  8.5 runs

Milwaukee Brewers:  39-35 (2nd place, NL Central)

Minnesota Twins:  36-37 (3rd place, AL Central)

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Milwaukee Brewers:  5-5 last 10

Minnesota Twins:  2-8 last 10

The Brewers won their 4-game series against the St Louis Cardinals 3-1. They enter this game with a 39-35 record overall and have a road record of 16-20. This is the series opener of a 3-game series with the Twins on Friday with the series finale of their series against the Chicago Cubs still to be played on Thursday. The Brewers lost the series opener of that series on Tuesday. Their offense ranks 24th in the MLB with a .679 OPS. Freddy Peralta is their starting pitcher on Thursday while rookie pitcher Jacob Misiorowski is making his start in this game on Friday. He is 1-0 with a 0.00 ERA this season. His team won their only game this season with him making an appearance. In his last MLB regular season start, he allowed 0 ER, 0 HR, and 4 BB with 5 SO on 0 hits through 5 IP against the St Louis Cardinals.

The Twins got swept in their 3-game series against the Houston Astros 3-0. They enter this game with a 36-37 record overall and have a home record of 20-12. This is the 1st game of a 3-game series with the Brewers on Friday with the series finale of their series against the Cincinnati Reds still to be played on Thursday. The Twins lost the 1st game of that series on Tuesday and the 2nd game on Wednesday. Their offense ranks 18th in the MLB with a .700 OPS. Chris Paddack is their starting pitcher on Thursday while Joe Ryan is making his start in this game on Friday. He is 7-2 with a 2.93 ERA this season. His team won 6 of their last 7 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 1 homer, and 2 walks with 7 strikeouts on 2 hits through 7 innings pitched against the Houston Astros.

The current betting odds have the Twins listed as a favorite in this game according to Draftkings Sportsbook. The Twins haven't looked great in their games this season with their 36-37 record overall, but that record has them right in the middle of the AL Central and in the Wild Card race. They have also looked a lot better in their own ballpark this year with their 20-12 home record. Meanwhile, the Brewers have looked good in their games this season with their 39-35 record overall which has them right near the top of the NL Central. They haven't been a great road team though with their 16-20 road record this season. The Twins haven't looked that great lately as they have been in a big slump, going 2-8 in their last 10 games, but this is a good game for them to bounce back now that they are back at home. Ryan is on the mound for the Twins in this one and he has been their ace this season. He is 7-2 with a 2.93 ERA and he hasn't been giving up many runs all season. He is coming off another good start in which he only gave up 2 earned runs which has been a common theme for him, and the team has had a ton of success with him starting too, winning 6 of the last 7 games he started in. The Brewers are going with Misiorowski in this one and he has looked good this year. He is 1-0 with a 0.00 ERA since he gave up no runs in his only start this year, but that was also against a slumping Cardinals team. He is also in his rookie season so he doesn't have a ton of experience pitching in the MLB and the Twins can take advantage of that with the more reliable starter here. The best way to place a bet here is on the Twins to win this game. 

Brewers Twins Prediction:  Our MLB Pick for Friday, June 20, 2025 (8:10 pm ET start time) is Twins 4 Brewers 2.

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Milwaukee Brewers: 30-16 (+13.3 units) on the moneyline against AL Central opponents. 82-85 (+17.2 units) on the moneyline as an underdog of +100 or higher. 105-93 (+17.9 units) on the moneyline in road games. 15-7 OVER on the road against AL Central opponents. 

Minnesota Twins: 17-23 (-12.3 units) on the moneyline against NL Central opponents. 112-86 (-11.2 units) on the moneyline in home games. 158-115 (-11.2 units) on the moneyline as a favorite of -110 or higher. 35-23 OVER as a home favorite of -150 to -200.

Milwaukee Brewers:  B. Woodruff (SP) Sixty Day IL - Shoulder. N. Cortes (SP) Sixty Day IL - Elbow. C. Thomas (SP) Sixty Day IL - Elbow. G. Mitchell (CF) Ten Day IL - Oblique. B. Perkins (CF) Sixty Day IL - Shin. R. Gasser (SP) Sixty Day IL - Elbow.

Minnesota Twins:  R. Jeffers (C) Day To Day - Arm. R. Lewis (3B) Ten Day IL - Hamstring. P. Lopez (SP) Sixty Day IL - Shoulder. Z. Matthews (SP) Fifteen Day IL - Shoulder. L. Keaschall (2B) Sixty Day IL - Forearm.

“We go from a count that could be 0-2 to a count that's 2-0. It is what it is.” - Rookie pitcher Chad Patrick after their loss against the Cubs in their game on Tuesday.

“He had an unbelievable season last year offensively. So it’s, from the beginning of this year to the end of the year before, you’re talking like a five-month gap. It’s the same guy. Not much has changed with him physically. He’s actually in a better spot than he was at the end of the season in a lot of ways. He has everything that he needs to keep working and keep trying to get that approach back.” - Rocco Baldelli after his team’s loss against the Reds in their game on Wednesday.

Sal Frelick (L) RF

Jackson Chourio (R) CF

Christian Yelich (L) DH

William Contreras (R) C

Brice Turang (L) 2B

Rhys Hoskins (R) 1B

Isaac Collins (S) LF

Caleb Durbin (R) 3B

Joey Ortiz (R) SS

Byron Buxton (R) CF

Matt Wallner (L) RF

Willi Castro (S) LF

Trevor Larnach (L) DH

Carlos Correa (R) SS

Ty France (R) 1B

Brooks Lee (S) 3B

Ryan Jeffers (R) C

Kody Clemens (L) 2B

Batting Average:  Sal Frelick (.289)

Hits:  Jackson Chourio (81)

Home Runs:  Christian Yelich (14)

RBI:  Christian Yelich (43)

Stolen Bases:  Brice Turang (16)

Wins:  Freddy Peralta (6)

Saves:  Trevor Megill (15)

ERA:  Aaron Ashby (0.00)

Batting Average:  Luke Keaschall (.368)

Hits:  Ty France (68)

Home Runs:  Byron Buxton (13)

RBI:  Byron Buxton (43)

Stolen Bases:  Byron Buxton (12)

Wins:  Joe Ryan (7)

Saves:  Jhoan Duran (10)

ERA:  Danny Coulombe (0.48)

Managers:

Milwaukee Brewers: Pat Murphy (2nd season)

Minnesota Twins: Rocco Baldelli (7th season)