Milwaukee Brewers vs Chicago Cubs Prediction, Preview and Odds - 06/19/2025

Game Time: 2:20 pm ET, Thursday, June 19, 2025

Venue:  Wrigley Field, Chicago, IL

Where to Watch:  MARQ

DraftKings:  Moneyline odds:  Brewers -105, Cubs -115; Over/Under:  8.5 runs

Bet365:  Moneyline odds:  Brewers -105, Cubs -115; Over/Under:  8.5 runs

BetMGM:  Moneyline odds:  Brewers -105, Cubs -115; Over/Under:  8.5 runs

Milwaukee Brewers:  39-35 (2nd place, NL Central)

Chicago Cubs:  45-28 (1st place, NL Central)

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Milwaukee Brewers:  5-5 last 10

Chicago Cubs:  6-4 last 10

The Brewers are entering this series off a win and won their 4-game series against the St Louis Cardinals 3-1 in their last series. They enter this game with a 39-35 record overall and have a road record of 16-20. This is the series finale of a 3-game series with the Cubs on Thursday with the 2nd game still to be played on Wednesday. The Brewers lost the series opener of this series on Tuesday. Their offense ranks 24th in the MLB with a .679 OPS. Rookie pitcher Jacob Misiorowski is their starting pitcher on Wednesday while Freddy Peralta is making his start in this game on Thursday. He is 6-4 with a 2.60 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 1 ER, 0 HR, and 1 BB with 6 SO on 4 hits through 6 IP against the St Louis Cardinals.

The Cubs are entering this series off a win and won their 4-game series against the Pittsburgh Pirates 3-1 in their last series. They enter this game with a 45-28 record overall and have a home record of 24-12. This is the 3rd game of a 3-game series with the Brewers on Thursday with the 2nd game of this series still to be played on Wednesday. The Cubs won the 1st game of this series on Tuesday. Their offense ranks 4th in the MLB with a .760 OPS. Jameson Taillon is their starting pitcher on Wednesday while rookie pitcher Cade Horton is making his start in this game on Thursday. He is 3-1 with a 3.47 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 1 walk with 4 strikeouts on 3 hits through 5.2 innings pitched against the Pittsburgh Pirates.

The current betting odds have the Brewers listed as a slight underdog in this game according to Draftkings Sportsbook. The Cubs have looked great in their games this season with their 45-28 record overall which has them right at the top of the NL Central with one of the best records in the entire MLB. They have also looked great in their own ballpark with their 24-12 home record this season. Meanwhile, the Brewers have looked good in their games this season with their 39-35 record overall which has them right near the top of the NL Central. They haven't been a good road team though with their 16-20 road record. The Brewers haven't looked their best lately, but this is a pitching matchup that they can take advantage of. Peralta is on the mound for the Brewers in this one and he has been one of their best starters this year. He is 6-4 with a 2.60 ERA and hasn't been giving up many runs all year. The team has lost 2 of the last 3 games he started in, but he only gave up 1 earned run in his last start which has been a common theme for him, and the team will be looking to get him a win against their division rivals here. The Cubs are going with Horton in this one and he is really inexperienced since he is still in his rookie year. He has looked good with his 3-1 record and his 3.47 ERA, but the team has still lost 2 games in a row with him starting and the Brewers will jump at this opportunity to take a game in this really important series with the division leaders. The best way to place a bet here is on the Brewers to win this game.

Brewers Cubs Prediction:  Our MLB Pick for Thursday, June 19, 2025 (2:20 pm ET start time) is Brewers 3 Cubs 2.

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Milwaukee Brewers: 224-178 (+27 units) on the moneyline in all games. 105-93 (+17.9 units) on the moneyline in road games. 82-85 (+17.2 units) on the moneyline as an underdog of +100 or higher. 29-12 UNDER when the money line is +125 to -125.

Chicago Cubs: 89-113 (-28.1 units) on the moneyline when the money line is +125 to -125. 88-78 (-5.1 units) on the moneyline vs. an NL team with a slugging percentage of .400 or worse on the season. 129-136 (-13.4 units) on the moneyline vs. a team with a good bullpen whose WHIP is 1.350 or better. 14-8 UNDER vs. poor power teams - averaging 0.9 or less HR's/game.

Milwaukee Brewers:  B. Woodruff (SP) Sixty Day IL - Shoulder. N. Cortes (SP) Sixty Day IL - Elbow. C. Thomas (SP) Sixty Day IL - Elbow. G. Mitchell (CF) Ten Day IL - Oblique. B. Perkins (CF) Sixty Day IL - Shin. R. Gasser (SP) Sixty Day IL - Elbow.

Chicago Cubs:  M. Amaya (C) Ten Day IL - Oblique. P. Hodge (RP) Fifteen Day IL - Oblique. E. Morgan (RP) Sixty Day IL - Elbow. S. Imanaga (SP) Fifteen Day IL - Leg. J. Assad (RP) Sixty Day IL - Oblique. J. Steele (SP) Sixty Day IL - Elbow.

“We go from a count that could be 0-2 to a count that's 2-0. It is what it is.” - Rookie pitcher Chad Patrick after their loss against the Cubs in their game on Tuesday.

“That’s why we come to the ballpark -- to see things like that, to see great players do great things, great players do amazing things.” - Craig Counsell after his team’s win against the Brewers in their game on Tuesday.

Sal Frelick (L) RF

Jackson Chourio (R) CF

William Contreras (R) C

Christian Yelich (L) DH

Rhys Hoskins (R) 1B

Isaac Collins (S) LF

Brice Turang (L) 2B

Caleb Durbin (R) 3B

Joey Ortiz (R) SS

Ian Happ (S) LF

Kyle Tucker (L) RF

Seiya Suzuki (R) DH

Pete Crow-Armstrong (L) CF

Dansby Swanson (R) SS

Michael Busch (L) 1B

Carson Kelly (R) C

Nico Hoerner (R) 2B

Matt Shaw (R) 3B

Batting Average:  Sal Frelick (.289)

Hits:  Jackson Chourio (81)

Home Runs:  Christian Yelich (14)

RBI:  Christian Yelich (43)

Stolen Bases:  Brice Turang (16)

Wins:  Freddy Peralta (6)

Saves:  Trevor Megill (15)

ERA:  Aaron Ashby (0.00)

Batting Average:  Nico Hoerner (.288)

Hits:  Nico Hoerner (77)

Home Runs:  Pete Crow-Armstrong (19)

RBI:  Seiya Suzuki (61)

Stolen Bases:  Pete Crow-Armstrong (23)

Wins:  Jameson Taillon (7)

Saves:  Daniel Palencia (7)

ERA:  Drew Pomeranz (0.00)

Managers:

Milwaukee Brewers: Pat Murphy (2nd season)

Chicago Cubs: Craig Counsell (2nd season)