Los Angeles Dodgers vs St Louis Cardinals Prediction, Preview and Odds - 06/07/2025

by Rod Pearson

Friday, Jun 06, 2025
Game Time: 2:15 pm ET, Saturday, June 7, 2025
Venue:  Busch Stadium, St. Louis, MO
Where to Watch:  FDSMW


Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Dodgers -187, Cardinals +152; Over/Under:  8 runs
Bet365:  Moneyline odds:  Dodgers -185, Cardinals +150; Over/Under:  8 runs
BetMGM:  Moneyline odds:  Dodgers -185, Cardinals +150; Over/Under:  8 runs

Season Record

Los Angeles Dodgers:  38-25 (1st place, NL West)
St Louis Cardinals:  34-28 (2nd place, NL Central)

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Recent Form
Los Angeles Dodgers:  6-4 last 10
St Louis Cardinals:  5-5 last 10



Los Angeles Dodgers vs St Louis Cardinals Preview and Analysis


The Dodgers are entering this series off a win and split their 4-game series against the New York Mets 2-2 in their last series. They enter this game with a 38-25 record overall and have a road record of 15-14. This is the 2nd game of a 3-game series with the Cardinals on Saturday with the series opener still to be played on Friday. Their offense ranks 1st in the MLB with a .806 OPS. Justin Wrobleski is their starting pitcher on Friday while Yoshinobu Yamamoto is making his start in this game on Saturday. He is 6-4 with a 2.39 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 ER, 1 HR, and 3 BB with 2 Ks on 7 hits through 3.2 IP against the New York Yankees.

The Cardinals are entering this series off a loss and lost their 3-game series against the Kansas City Royals 2-1 in their last series. They enter this game with a 34-28 record overall and have a home record of 20-10. This is the 2nd game of a 3-game series with the Dodgers on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 10th in the MLB with a .724 OPS. Sonny Gray is their starting pitcher on Friday while Erick Fedde is making his start in this game on Saturday. He is 3-5 with a 3.82 ERA this season. His team lost their last 4 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 0 homers, and 3 BB with 5 strikeouts on 4 hits through 6 innings played against the Texas Rangers.


Dodgers vs Cardinals Prediction

The current betting odds have the Dodgers listed as a favorite in this game according to Draftkings Sportsbook. The Dodgers have looked really good in their games this season with their 38-25 record overall which has them right at the top of the NL West. They haven't been a great road team though with their 15-14 road record. Meanwhile, the Cardinals have looked good in their games this season with their 34-28 record overall which has them right near the top of the NL Central. They have also looked great in their own ballpark with their 20-10 home record this year. Neither team has looked great lately, but the Dodgers have been the slightly hotter team lately as they are 6-4 in their last 10 games. They also have the better pitching matchup in this one and can take advantage of that as the Cardinals have started cooling off now. Fedde is on the mound for the Cardinals in this one and he has looked good this season. He is 3-5 with a 3.82 ERA this year and hasn't been giving up a ton of runs in his starts, only giving up 2 earned runs in his last start, but the Dodgers do have one of the best offenses in the MLB. The Cardinals haven't had a ton of success with Fedde on the mound either, the team losing 4 games in a row now with him starting. Yamamoto is starting for the Dodgers in this one and he has looked great this season. He is 6-4 with a 2.39 ERA and hasn't been giving up many runs all year. He did give up 4 earned runs in his last start, but that hasn't been a common theme for him this year and he will be looking to bounce back in this one. The team has also won 3 of their last 4 games with him starting and they have the better offense to put up runs too. The best way to place a bet here is on the Dodgers to win this game. 

Dodgers Cardinals Prediction:  Our MLB Pick for Saturday, June 7, 2025 (2:15 pm ET start time) is Dodgers 6 Cardinals 2.
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MLB Betting Trends


Los Angeles Dodgers: 173-106 (+14.1 units) on the moneyline against right-handed starters. 216-121 (+7.5 units) on the moneyline as a favorite of -110 or higher. 62-41 (+9.7 units) on the moneyline when playing against a good team (Win Pct. 54% to 62%). 60-37 OVER when playing against a good team (Win Pct. 54% to 62%). 

St Louis Cardinals: 187-198 (-23.1 units) on the moneyline in all games. 99-93 (-16.9 units) on the moneyline in home games. 135-143 (-14.5 units) on the moneyline against right-handed starters. 22-13 OVER vs. a team with a good bullpen whose WHIP is 1.350 or better.

Key Injuries


Los Angeles Dodgers:  L. Garcia (RP) Fifteen Day IL - Adductor. T. Glasnow (SP) Sixty Day IL - Shoulder. E. Phillips (RP) Sixty Day IL - Forearm. K. Yates (RP) Fifteen Day IL - Hamstring. B. Snell (SP) Sixty Day IL - Shoulder. R. Sasaki (SP) Fifteen Day IL - Shoulder. B. Treinen (RP) Sixty Day IL - Forearm. M. Kopech (RP) Sixty Day IL - Shoulder. E. Henriquez (SP) Sixty Day IL - Foot. K. Hurt (SP) Sixty Day IL - Elbow. E. Sheehan (SP) Sixty Day IL - Elbow. M. Grove (RP) Sixty Day IL - Shoulder. B. Graterol (RP) Sixty Day IL - Shoulder. R. Ryan (SP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder.

St Louis Cardinals:  M. Liberatore (SP) Day To Day - Fatigue. J. Walker (RF) Ten Day IL - Wrist. Z. Thompson (RP) Sixty Day IL - Lat.


Notable Quotes


"He's been working hard. We haven't seen that lined ball to left field in quite some time. That speaks to a direct path, through the ball, bat in the hitting zone for a long time. That was a good thing. I hope that we've unlocked something." - Dave Roberts after his team’s win against the Mets in their game on Thursday.


“I love the intensity that he brings and he’s as much of a bulldog out there as anyone I’ve ever played with.” - Miles Mikolas after their win against the Royals in their game on Thursday.


Starting Lineups


Los Angeles Dodgers
Shohei Ohtani (L) DH
Mookie Betts (R) SS
Will Smith (R) C
Teoscar Hernández (R) RF
Andy Pages (R) CF
Tommy Edman (S) 2B
Enrique Hernández (R) 1B
Michael Conforto (L) LF
Miguel Rojas (R) 3B

St Louis Cardinals
Lars Nootbaar (L) LF
Masyn Winn (R) SS
Brendan Donovan (L) 2B
Willson Contreras (R) 1B
Iván Herrera (R) DH
Nolan Arenado (R) 3B
Yohel Pozo (R) C
Ryan Vilade (R) RF
Victor Scott II (L) CF

Statistical Leaders


Los Angeles Dodgers
Batting Average:  Hyeseong Kim (.404)
Hits:  Shohei Ohtani (72)
Home Runs:  Shohei Ohtani (23)
RBI:  Teoscar Hernández (43)
Stolen Bases:  Shohei Ohtani (11)
Wins:  Yoshinobu Yamamoto (6)
Saves:  Tanner Scott (11)
ERA:  Evan Phillips (0.00)

St Louis Cardinals
Batting Average:  Thomas Saggese (.341)
Hits:  Brendan Donovan (72)
Home Runs:  Lars Nootbaar (8)
RBI:  Willson Contreras (36)
Stolen Bases:  Victor Scott (17)
Wins:  Sonny Gray (6)
Saves:  Ryan Helsley (13)
ERA:  Michael McGreevy (0.00)

Managers:
Los Angeles Dodgers: Dave Roberts (10th season)
St Louis Cardinals: Oliver Marmol (4th season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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