Los Angeles Dodgers vs San Diego Padres Prediction, Preview and Odds - 06/11/2025

by Rod Pearson

Tuesday, Jun 10, 2025
Game Time: 4:10 pm ET, Wednesday, June 11, 2025
Venue:  Petco Park, San Diego, CA 
Where to Watch:  PADRES.tv


Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Dodgers -144, Padres +118; Over/Under:  9.5 runs
Bet365:  Moneyline odds:  Dodgers -145, Padres +120; Over/Under:  9.5 runs
BetMGM:  Moneyline odds:  Dodgers -145, Padres +120; Over/Under:  9.5 runs

Season Record

Los Angeles Dodgers:  40-27 (1st place, NL West)
San Diego Padres:  37-28 (3rd place, NL West)

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Recent Form
Los Angeles Dodgers:  5-5 last 10
San Diego Padres:  5-5 last 10



Los Angeles Dodgers vs San Diego Padres Preview and Analysis


The Dodgers are entering this series off a win and lost their 3-game series against the St Louis Cardinals 2-1 in their last series. They enter this game with a 40-27 record overall and have a road record of 17-16. This is the series finale of a 3-game series with the Padres on Wednesday with the 2nd game still to be played on Tuesday. The Dodgers won the series opener on Monday. Their offense ranks 2nd in the MLB with a .802 OPS. Matt Sauer is their starting pitcher on Tuesday while Justin Wrobleski is making his start in this game on Wednesday. He is 1-2 with a 7.20 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 ER, 1 HR, and 3 BB with 5 Ks on 6 hits through 6 IP against the St Louis Cardinals.

The Padres are entering this series off a win and won their 3-game series against the Milwaukee Brewers 2-1 in their last series. They enter this game with a 37-28 record overall and have a home record of 20-11. This is the 3rd game of a 3-game series with the Dodgers on Wednesday with the 2nd game of this series still to be played on Tuesday. The Padres lost the 1st game of this series on Monday. Their offense ranks 22nd in the MLB with a .686 OPS. Dylan Cease is their starting pitcher on Tuesday while Randy Vásquez is making his start in this game on Wednesday. He is 3-4 with a 3.69 ERA this season. His team won their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 4 BB with 2 strikeouts on 2 hits through 4.2 innings played against the Milwaukee Brewers.


Dodgers vs Padres Prediction

The current betting odds have the Padres listed as an underdog in this game according to Draftkings Sportsbook. The Padres have looked really good in their games this season with their 37-28 record overall which has them right near the top of the NL West. They have also looked great in their own ballpark this year with their 20-11 home record. Meanwhile, the Dodgers have looked really good in their games this season with their 40-27 record overall which has them right at the top of the NL West. They haven't been a great road team though with their 17-16 road record this season. The Dodgers took the first game of this series, but neither team has been rolling lately and this is definitely a pitching matchup that the Padres can take advantage of. The Padres are going with Vasquez in this one and he has looked great this season. He is 3-4 with a 3.69 ERA and he hasn't been giving up many runs lately. He gave up no runs in his last start and his team has had a ton of success with him lately, winning the last 3 games that he started in. Wrobleski is on the mound for the Dodgers here and he hasn't looked great this year. He is 1-2 with a 7.20 ERA and he gave up 4 earned runs in his last start which has been a common theme for him. His team has also lost 2 of the last 3 games that he started in and the Dodgers have struggled a lot more as a team on the road this season. The best way to place a bet here is on the Padres to win this game. 

Dodgers Padres Prediction:  Our MLB Pick for Wednesday, June 11, 2025 (4:10 pm ET start time) is Padres 6 Dodgers 1.
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MLB Betting Trends


Los Angeles Dodgers: 175-108 (+13.3 units) on the moneyline against right-handed starters. 187-122 (+5 units) on the moneyline vs. good fielding teams - averaging 0.6 errors/game or less. 64-43 (+8.9 units) on the moneyline when playing against a good team (Win Pct. 54% to 62%). 7-4 UNDER against division opponents.

San Diego Padres: 110-85 (-10.2 units) on the moneyline in home games. 70-80 (-14 units) on the moneyline when the money line is +125 to -125. 54-60 (-7.4 units) on the moneyline when playing against a good team (Win Pct. 54% to 62%). 23-11 UNDER vs. a team with a good bullpen whose WHIP is 1.350 or better.

Key Injuries


Los Angeles Dodgers:  T. Gonsolin (SP) Fifteen Day IL - Elbow. L. Garcia (RP) Fifteen Day IL - Adductor. T. Glasnow (SP) Sixty Day IL - Shoulder. E. Phillips (RP) Sixty Day IL - forearm. B. Snell (SP) Sixty Day IL - Shoulder. R. Sasaki (SP) Fifteen Day IL - Shoulder. B. Treinen (RP) Sixty Day IL - Forearm. E. Henriquez (SP) Sixty Day IL - Foot. K. Hurt (SP) Sixty Day IL - Elbow. E. Sheehan (SP) Sixty Day IL - Elbow. M. Grove (RP) Sixty Day IL - Shoulder. B. Graterol (RP) Sixty Day IL - Shoulder. R. Ryan (SP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder.

San Diego Padres:  M. King (SP) Fifteen Day IL - Shoulder. J. Heyward (LF) Ten Day IL - Oblique. L. Gillaspie (RP) Fifteen Day IL - Oblique. B. Hoeing (RP) Sixty Day IL - Shoulder. J. Brito (RP) Sixty Day IL - Forearm. Y. Darvish (SP) Fifteen Day IL - Elbow. J. Musgrove (SP) Sixty Day IL - Elbow.


Notable Quotes


"The fans, certainly, they’re always into it. You’ve got two good ballclubs. I think the way you saw Mike [Shildt] manage with some urgency and kind of the moves -- I wouldn’t say playoff game, but it was intense. It was fun out there." - Dave Roberts after his team’s win against the Padres in their game on Monday.


“It was back and forth. They punch, we punch -- it’s a typical game we play against them. And many more to come.” - Mike Shildt after his team’s loss against the LA Dodgers in their game on Monday.


Starting Lineups


Los Angeles Dodgers
Shohei Ohtani (L) DH
Mookie Betts (R) SS
Freddie Freeman (L) 1B
Teoscar Hernández (R) RF
Will Smith (R) C
Max Muncy (L) 3B
Andy Pages (R) LF
Tommy Edman (S) 2B
Hyeseong Kim (L) CF

San Diego Padres
Fernando Tatis Jr. (R) RF
Luis Arraez (L) 1B
Manny Machado (R) 3B
Jackson Merrill (L) CF
Gavin Sheets (L) DH
Xander Bogaerts (R) SS
Jake Cronenworth (L) 2B
Tyler Wade (L) LF
Elias Díaz (R) C

Statistical Leaders


Los Angeles Dodgers
Batting Average:  Hyeseong Kim (.410)
Hits:  Shohei Ohtani (76)
Home Runs:  Shohei Ohtani (23)
RBI:  Teoscar Hernández (44)
Stolen Bases:  Shohei Ohtani (11)
Wins:  Yoshinobu Yamamoto (6)
Saves:  Tanner Scott (12)
ERA:  Evan Phillips (0.00)

San Diego Padres
Batting Average:  Manny Machado (.320)
Hits:  Manny Machado (78)
Home Runs:  Fernando Tatis (13)
RBI:  Gavin Sheets (38)
Stolen Bases:  Fernando Tatis (13)
Wins:  Nick Pivetta (6)
Saves:  Robert Suarez (21)
ERA:  Bradgley Rodriguez (0.00)

Managers:
Los Angeles Dodgers: Dave Roberts (10th season)
San Diego Padres: Mike Shildt (2nd season)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

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