Cincinnati Bengals vs Pittsburgh Steelers Prediction, Odds and Preview - 09/26/2021

by Amedeus Mastrangelo

Tuesday, Sep 21, 2021
Game Time: 1:00 pm ET, Sunday, September 26, 2021
Venue:  Heinz Field, Pittsburgh, PA 
Where to Watch:  CBS

 

Opening Odds at USA Sportsbooks

DraftKings:  Point Spread:  Bengals +4.5, Steelers -4.5; Over/Under:  44 points
Bet365:  Point Spread:  Bengals +4.5, Steelers -4.5; Over/Under:  44 points
BetMGM:  Point Spread:  Bengals +4.5, Steelers -4.5; Over/Under:  44 points
 

Season Record

Cincinnati Bengals:  1-1 (4th place, AFC North)
Pittsburgh Steelers:  1-1 (1st place, NFC East)
 
Do not miss out on our expert handicapper analysis! Larry Ness has a CFB/NFL start to 2021 of 20-12, +$6,377 profit! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

 

Cincinnati Bengals vs Pittsburgh Steelers Preview and Analysis

 
Recent Form
Cincinnati Bengals:  lost on the road on Sep. 19 against the Chicago Bears 20-17.
Pittsburgh Steelers:  lost at home on Sep. 19 against the Las Vegas Raiders 26-17.
 
 
 

Cincinnati Bengals Analysis

The Bengals are coming into this game with a 1-1 record overall and are 0-1 in their road games where they will be in this game. They won their first game of the season in overtime against the Minnesota Vikings and went on to lose to the Chicago Bears in their last game. Joe Burrow struggled a lot in that game as he completed 19/30 passes for 207 yards, 2 touchdowns, and 3 interceptions. Joe Mixon was the only player that rushed the ball in that game as he had 69 yards on 20 carries. Tyler Boyd led the receivers with 73 yards on 7 receptions while Tee Higgins was right behind him with 60 yards and 1 touchdown on 6 receptions. Sam Hubbard led the defense with 5 solo tackles and 2 assisted ones also recording 0.5 sacks in that game. D.J. Reader had 1 sack in that one and Trey Hendrickson led the defense in sacks with 1.5. Logan Wilson caught the only interception for them in that game. They have scored 44 points in their first 2 games and they have allowed their opponents to score 44 points against them. Their offense has accumulated 614 yards this season while their defense has allowed 609 yards against them.
 
 

Pittsburgh Steelers Analysis

The Steelers are coming into this game with a 1-1 record overall and they are 0-1 at home this season where they will be in this game. They won their first game of the season in an upset fashion against the Buffalo Bills and then came home last week and got upset by the Las Vegas Raiders in their last game. Ben Roethlisberger played alright in that game as he completed 27/40 passes for 295 yards, 1 touchdown and 1 interception. They did not have much of a run game as Najee Harris led the team in rushing with 38 yards on 10 carries. The receiving corps had a good day as Diontae Johnson led the team in receiving with 105 yards on 9 receptions while Chase Claypool was right behind him with 70 receiving yards on 3 receptions. Robert Spillane led the defense with 8 solo tackles and 2 assisted ones. T.J. Watt and Melvin Ingram each recorded 1 sack in that game while no one on the defense had an interception. They have scored 40 points in their first 2 games of the season and they have allowed their opponents to score 42 points against them. Pittsburgh’s offense has accumulated 583 yards this season while the Steelers’ defense has allowed 796 yards against them.
 
 

 

Bengals vs Steelers Prediction

Big Ben is dealing with a Pectoral issue right now and if he does not play in this game then they will be in real trouble. This is a divisional matchup so this will be a grindy and physical game between these 2 teams that hate each other. All the Steelers have is a good defense so they will likely not score a lot, especially if Big Ben is injured. The Bengals also do not score a lot of points so the best bets to place in this game would be on the Bengals to cover the spread and on the under as this should be a lower scoring game.
 
Bengals Steelers Prediction:  Our NFL Pick for Sunday, September 26, 2021 (1:00 pm ET start time) is Bengals 17 Steelers 13.
Don't miss our champion handicappers betting insights, free picks and expert football picks today.  And if you enjoyed this Cincinnati Bengals Pittsburgh Steelers prediction, be sure to drop by every day for our weekly NFL predictions and previews.
 

NFL Betting Trends

 
Cincinnati Bengals: 16-17 ATS in all games. 6-9 ATS off 1 or more consecutive unders.
Pittsburgh Steelers: 18-15 ATS in all games. 7-5 ATS as a home favorite of 7 points or less.
 

Key Injuries

 
Cincinnati Bengals:  X. Su'a-Filo (G) day-to-day - Leg injury. T. Waynes (CB) day-to-day - Hamstring injury. R. Allen (S) Out indefinitely - Hamstring injury.
Pittsburgh Steelers:  T. Alualu (DE) I-R - Ankle injury. D. Johnson (WR) day-to-day - Knee injury. D. Haskins Jr. (QB) day-to-day - Face injury.
 

Players to Watch

 
Cincinnati Bengals: Ja’Marr Chase is one player to watch in this game. He leads his team in receiving yards and in touchdowns. He will need to make some big catches in the end zone here to help his team pull off a big upset as underdogs.
 
Pittsburgh Steelers: Najee Harris is one player to watch here. He leads the team in rushing but he has not had a big explosive game yet. This is the perfect opportunity for him to breakout in this game especially if their quarterback is injured. Look for him to relieve some of that pressure and break off some big runs in this game.
 

Notable Quotes

"That's just me trying to force the ball trying to get something going. You learned a lesson today that when your defense is playing as good as they are, you don't have to force those balls. You kind of just let the game come to you." - Joe Burrow on his poor performance with 3 interceptions against the Bears in week 2.
 
 
"I'm not going to say London Bridge is falling down, but we've got to grow from this. We've got to keep harping on our mistakes and understand how big those (get off) plays are." - Cam Heyward on how the defense must keep improving after a home loss to the Raiders in week 2.
 
 

Starting Lineups

 
Cincinnati Bengals
WR Chase, Ja'Marr 
WR Boyd, Tyler 
WR Higgins, Tee 
TE Uzomah, CJ 
QB Burrow, Joe 
RB Mixon, Joe  
 
Pittsburgh Steelers
WR Smith-Schuster, JuJu 
WR Claypool, Chase 
WR Johnson, Diontae 
TE Ebron, Eric 
QB ROETHLISBERGER, BEN 
RB Harris, Najee 
FB Watt, Derek 

Statistical Leaders

 
Cincinnati Bengals
Passing: J. Burrow (468)
Rushing: J. Mixon (196)
Receiving: J. Chase (155)
Touchdowns: J. Chase (2)
Sacks: B. Hill (2)
Tackles: J. Bates III (10)
 
Pittsburgh Steelers
Passing: B. Roethlisberger (483)
Rushing: N. Harris (83)
Receiving: D. Johnson (141)
Touchdowns: D. Johnson (1)
Sacks: T. Watt (3)
Tackles: J. Pierre (12)
 
Coaches:
Cincinnati Bengals: Zac Taylor (3rd season)
Pittsburgh Steelers: Mike Tomlin (15th season)
 

Weather Forecast

66 degrees F mostly sunny, 66% humidity, 0% chance of rain, up to 11 mph wind speeds W.


Amedeus Mastrangelo

About the Author:

Amedeus Mastrangelo has been heavily wagering on all sports for years and plays just about everything, including sides, totals, favorites, underdogs, against the spread, alternative spreads, first half, second half, player props, and futures. The bottom line is, if Mastrangelo can see an edge in any way shape or form, then he's going to take advantage.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2025 Al McMordie's BigAl.com. All Rights Reserved.