Chicago Cubs vs Philadelphia Phillies Prediction, Preview and Odds - 06/11/2025

Game Time: 1:05 pm ET, Wednesday, June 11, 2025

Venue:  Citizens Bank Park, Philadelphia, PA 

Where to Watch:  MLBN

DraftKings:  Moneyline odds:  Cubs +104, Phillies -126; Over/Under:  9 runs

Bet365:  Moneyline odds:  Cubs +105, Phillies -125; Over/Under:  9 runs

BetMGM:  Moneyline odds:  Cubs +105, Phillies -125; Over/Under:  9 runs

Chicago Cubs:  40-26 (1st place, NL Central)

Philadelphia Phillies:  38-28 (2nd place, NL East)

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Chicago Cubs:  5-5 last 10

Philadelphia Phillies:  2-8 last 10

The Cubs are entering this series off a loss and lost their 3-game series against the Detroit Tigers 2-1 in their last series. They enter this game with a 40-26 record overall and have a road record of 20-15. This is the series finale of a 3-game series with the Phillies on Wednesday with the 2nd game still to be played on Tuesday. The Cubs lost the series opener on Monday. Their offense ranks 4th in the MLB with a .770 OPS. Colin Rea is their starting pitcher on Tuesday while Ben Brown is making his start in this game on Wednesday. He is 3-4 with a 5.37 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 ER, 1 HR, and 1 BB with 7 Ks on 7 hits through 7 IP against the Detroit Tigers.

The Phillies are entering this series off a loss and got swept in their 3-game series against the Pittsburgh Pirates 3-0 in their last series. They enter this game with a 38-28 record overall and have a home record of 20-12. This is the 3rd game of a 3-game series with the Cubs on Wednesday with the 2nd game of this series still to be played on Tuesday. The Phillies won the 1st game of this series on Monday. Their offense ranks 9th in the MLB with a .725 OPS. Rookie pitcher Mick Abel is their starting pitcher on Tuesday while Jesús Luzardo is making his start in this game on Wednesday. He is 5-2 with a 4.46 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 8 earned runs, 1 homer, and 2 BB with 2 strikeouts on 9 hits through 2.1 innings played against the Toronto Blue Jays.

The current betting odds have the Cubs listed as a slight underdog in this game according to Draftkings Sportsbook. The Phillies have looked good in their games this season with their 38-28 record overall which has them right near the top of the NL East. They have also looked a lot better in their own ballpark with their 20-12 home record. Meanwhile, the Cubs have looked really good in their games this season with their 40-26 record overall which has them right at the top of the NL Central with one of the best records in the entire MLB. They have also been a good road team this year with their 20-15 road record. The Cubs lost the 1st game of this series and haven't looked great lately as they are 5-5 in their last 10 games, but the Phillies have been worse as they are 2-8 in their last 10 games and this is a pitching matchup that the Cubs can take advantage of. Luzardo is on the mound for the Phillies in this one and he hasn't looked great in his starts lately. He is 5-2 with a 4.46 ERA and he is coming off a terrible start in which he gave up 8 earned runs in around 2 innings. His team has also lost 3 games in a row now with him starting and the Cubs do have one of the best offenses in the entire MLB. Brown is on the mound for the Cubs and he has looked better in his starts lately. He is 3-4 with a 5.37 ERA, but he only gave up 2 earned runs in his last start and the team has had more success with him lately, winning 2 of the last 3 games he started in. The Phillies took the series opener, but they have been in a big slump lately and Luzardo is in for a long night against this Cubs offense. The best way to place a bet here is on the Cubs to win this game. 

Cubs Phillies Prediction:  Our MLB Pick for Wednesday, June 11, 2025 (1:05 pm ET start time) is Cubs 9 Phillies 3.

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Chicago Cubs: 36-44 (-13.4 units) on the moneyline against NL East opponents. 88-111 (-26.9 units) on the moneyline when the money line is +125 to -125. 83-76 (-7.9 units) on the moneyline vs. a team slugging percentage .400 or worse on the season (NL). 20-10 OVER on the road when playing against a good team (Win Pct. 54% to 62%).

Philadelphia Phillies: 187-113 (+13.1 units) on the moneyline as a favorite of -110 or higher. 130-73 (+19.3 units) on the moneyline in home games. 157-113 (+9.2 units) on the moneyline against right-handed starters. 16-8 OVER at home vs. a starting pitcher whose lasts less than 5 innings per start.

Chicago Cubs:  M. Amaya (C) Ten Day IL - Oblique. P. Hodge (RP) Fifteen Day IL - Oblique. E. Morgan (RP) Sixty Day IL - Elbow. S. Imanaga (SP) Fifteen Day IL - Leg. J. Assad (RP) Sixty Day IL - Oblique. J. Steele (SP) Sixty Day IL - Elbow.

Philadelphia Phillies:  B. Harper (1B) Ten Day IL - Wrist. A. Nola (SP) Fifteen Day IL - Ankle.

“We gave up 16 hits and only four runs. We were kind of working out of some jams and we got some double plays to get out of stuff. We did a nice job. Ultimately, we had five hits in 11 innings. That’s probably not going to create a lot of offense. We got it tied and had a shot, and they had a good 11th.” - Craig Counsell after his team’s loss against the Phillies in their game on Monday.

"We had 19 baserunners tonight and scored four runs. That's kind of hard to do." - Rob Thomson after his team’s win against the Cubs in their game on Monday.

Ian Happ (S) LF

Kyle Tucker (L) RF

Seiya Suzuki (R) DH

Pete Crow-Armstrong (L) CF

Dansby Swanson (R) SS

Michael Busch (L) 1B

Carson Kelly (R) C

Nico Hoerner (R) 2B

Matt Shaw (R) 3B

Trea Turner (R) SS

Kyle Schwarber (L) DH

Alec Bohm (R) 1B

Nick Castellanos (R) RF

J.T. Realmuto (R) C

Edmundo Sosa (R) 2B

Otto Kemp (R) 3B

Weston Wilson (R) LF

Johan Rojas (R) CF

Batting Average:  Nico Hoerner (.281)

Hits:  Pete Crow-Armstrong (72)

Home Runs:  Pete Crow-Armstrong (17)

RBI:  Seiya Suzuki (55)

Stolen Bases:  Pete Crow-Armstrong (21)

Wins:  Jameson Taillon (6)

Saves:  Daniel Palencia (5)

ERA:  Drew Pomeranz (0.00)

Batting Average:  Otto Kemp (.300)

Hits:  Trea Turner (79)

Home Runs:  Kyle Schwarber (20)

RBI:  Kyle Schwarber (46)

Stolen Bases:  Trea Turner (17)

Wins:  Zack Wheeler (6)

Saves:  Jordan Romano (8)

ERA:  Mick Abel (0.79)

Managers:

Chicago Cubs: Craig Counsell (2nd season)

Philadelphia Phillies: Rob Thomson (4th season)