by Rod Pearson
Tuesday, May 20, 2025
Game Time: 10:10 pm ET, Wednesday, May 21, 2025
Venue: Dodger Stadium, Los Angeles, CA
Where to Watch: Sportsnet LA
Opening Odds at USA Sportsbooks
DraftKings: Moneyline odds: Diamondbacks +114, Dodgers -135; Over/Under: 9 runs
Bet365: Moneyline odds: Diamondbacks +115, Dodgers -135; Over/Under: 9 runs
BetMGM: Moneyline odds: Diamondbacks +115, Dodgers -135; Over/Under: 9 runs
Season Record
Arizona Diamondbacks: 26-22 (4th place, NL West)
Los Angeles Dodgers: 29-19 (1st place, NL West)
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Recent Form
Arizona Diamondbacks: 6-4 last 10
Los Angeles Dodgers: 4-6 last 10
Arizona Diamondbacks vs Los Angeles Dodgers Preview and Analysis
The Diamondbacks are entering this series off a win and won their 3-game series against the Colorado Rockies 2-1 in their last series. They enter this game with a 26-22 record overall and have a road record of 13-9. This is the series finale of a 3-game series with the Dodgers on Wednesday with the 2nd game still to be played on Tuesday. The Diamondbacks won the series opener on Monday. Their offense ranks 3rd in the MLB with a .789 OPS. Ryne Nelson is their starting pitcher on Tuesday while Corbin Burnes is making his start in this game on Wednesday. He is 3-1 with a 2.56 ERA this season. His team won their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 0 ER, 0 HR, and 3 BB with 10 Ks on 2 hits through 6 IP against the Colorado Rockies.
The Dodgers are entering this series off a loss and got swept in their 3-game series against the Los Angeles Angels 3-0 in their last series. They enter this game with a 29-19 record overall and have a home record of 17-8. This is the 3rd game of a 3-game series with the Diamondbacks on Wednesday with the 2nd game still to be played on Tuesday. The Dodgers lost the 1st game of this series on Monday. Their offense ranks 1st in the MLB with a .822 OPS. Yoshinobu Yamamoto is their starting pitcher on Tuesday while Dustin May is making his start in this game on Wednesday. He is 1-4 with a 4.43 ERA this season. His team lost their last 3 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 4 earned runs, 1 homer, and 2 BB with 8 strikeouts on 6 hits through 5 innings played against the Los Angeles Angels.
Diamondbacks vs Dodgers Prediction
The current betting odds have the Diamondbacks listed as an underdog in this game according to Draftkings Sportsbook. The Diamondbacks have looked good in their games this season with their 26-22 record overall, but that record has them right near the bottom of their division due to such a tough NL West. They haven't been a bad road team though with their 13-9 road record. Meanwhile, the Dodgers have looked really good in their games this season with their 29-19 record overall which has them right at the top of their division. They have also looked great in their own ballpark this year with their 17-8 home record. The Dodgers are a powerhouse this year, but they aren't going to win every game and lately they haven't looked that good. They just got swept by the Angels in their last series and are only 4-6 in their last 10 games while the Diamondbacks are 6-4. The Dodgers don't have a great pitching matchup here either as they are going with May who is 1-4 with a 4.43 ERA this season. He has been giving up a lot of runs this season, even giving up 4 earned runs in his last start, and the team hasn't had a lot of success with him either, losing the last 3 games he started. Burnes is on the mound for the Diamondbacks and he is 3-1 with a 2.56 ERA this season. He has looked great this year as he hasn't been giving up many runs in any of his starts, and that has been a common theme for him throughout his career. He is coming off a start in which he gave up no runs too, and the team has won their last 3 games with him starting. The best way to place a bet here is on the Diamondbacks to win this game.
Diamondbacks Dodgers Prediction: Our MLB Pick for Wednesday, May 21, 2025 (10:10 pm ET start time) is Diamondbacks 6 Dodgers 3.
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MLB Betting Trends
Arizona Diamondbacks: 88-97 (+16.8 units) on the moneyline as an underdog of +100 or higher. 105-88 (+28.4 units) on the moneyline in road games. 142-121 (+19 units) on the moneyline against right-handed starters. 38-20 OVER on the road vs. good power teams - averaging 1.25 or more HR's/game.
Los Angeles Dodgers: 6-7 (-4.6 units) on the moneyline as a favorite of -125 to -175. 6-11 (-13.3 units) on the moneyline when the total is 9 to 9.5. 16-14 (-9 units) on the moneyline vs. a team with a poor bullpen whose ERA is 4.20 or worse. 26-10 OVER vs. an NL starting pitcher whose ERA is 3.20 or better.
Key Injuries
Arizona Diamondbacks: E. Rodriguez (SP) Fifteen Day IL - Shoulder. J. Martinez (RP) Fifteen Day IL - Shoulder. A. Puk (RP) Sixty Day IL - Elbow. J. Montgomery (SP) Sixty Day IL - Elbow. B. Walston (SP) Sixty Day IL - Elbow.
Los Angeles Dodgers: K. Yates (RP) Fifteen Day IL - Hamstring. B. Snell (SP) Sixty Day IL - Shoulder. R. Sasaki (SP) Fifteen Day IL - Shoulder. E. Phillips (RP) Fifteen Day IL - forearm. B. Treinen (RP) Sixty Day IL - Forearm. M. Kopech (RP) Sixty Day IL - Shoulder. T. Glasnow (SP) Fifteen Day IL - Shoulder. E. Henriquez (SP) Sixty Day IL - Foot. K. Hurt (SP) Sixty Day IL - Elbow. E. Sheehan (SP) Sixty Day IL - Elbow. M. Grove (RP) Sixty Day IL - Shoulder. B. Graterol (RP) Sixty Day IL - Shoulder. R. Ryan (SP) Sixty Day IL - Elbow. G. Stone (SP) Sixty Day IL - Shoulder.
Notable Quotes
“First of all, adaptability is a word inside of our [team] culture. So our guys just made that adjustment, and they said, ‘We can handle it, we’ll just have good at-bats, whether it's against the lefty or the righty, and trust the lineup and the guy hitting behind me,’ and it really worked out.” - Torey Lovullo after his team’s win against the LA Dodgers in their game on Monday.
"I think right at that point in time, he's just trying to find the baseball and not really letting the guys to the side know that he is having trouble. But that's more experience and kind of an outlier play." - Dave Roberts after his team’s loss against the Diamondbacks in their game on Monday.
Starting Lineups
Arizona Diamondbacks
Ketel Marte (S) 2B
Corbin Carroll (L) RF
Lourdes Gurriel Jr. (R) LF
Eugenio Suárez (R) 3B
Josh Naylor (L) 1B
Gabriel Moreno (R) C
Tim Tawa (R) CF
Pavin Smith (L) DH
Geraldo Perdomo (S) SS
Los Angeles Dodgers
Shohei Ohtani (L) DH
Mookie Betts (R) SS
Freddie Freeman (L) 1B
Will Smith (R) C
Teoscar Hernández (R) RF
Max Muncy (L) 3B
Michael Conforto (L) LF
Tommy Edman (S) 2B
Hyeseong Kim (L) CF
Statistical Leaders
Arizona Diamondbacks
Batting Average: Pavin Smith (.306)
Hits: Corbin Carroll (56)
Home Runs: Corbin Carroll (14)
RBI: Eugenio Suárez (38)
Stolen Bases: Geraldo Perdomo (11)
Wins: Brandon Pfaadt (7)
Saves: Shelby Miller (5)
ERA: Scott McGough (0.00)
Los Angeles Dodgers
Batting Average: Hyeseong Kim (.400)
Hits: Shohei Ohtani (58)
Home Runs: Shohei Ohtani (17)
RBI: Teoscar Hernández (35)
Stolen Bases: Shohei Ohtani (10)
Wins: Yoshinobu Yamamoto (5)
Saves: Tanner Scott (9)
ERA: Evan Phillips (0.00)
Managers:
Arizona Diamondbacks: Torey Lovullo (9th season)
Los Angeles Dodgers: Dave Roberts (10th season)
Rod Pearson
About the Author:
Rod Pearson has been a rabid sports fan his entire life. He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years. In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective. Join Rod every day as he breaks down the games to find the best betting value.
