Seattle Mariners vs Los Angeles Angels Prediction, Preview and Odds - 07/26/2025

by Rod Pearson

Friday, Jul 25, 2025
Game Time: 9:38 pm ET, Saturday, July 26, 2025
Venue:  Angel Stadium, Anaheim, CA 
Where to Watch:  MLBN


Opening Odds at USA Sportsbooks

DraftKings:  Moneyline odds:  Mariners -150, Angels +123; Over/Under:  8.5 runs
Bet365:  Moneyline odds:  Mariners -150, Angels +125; Over/Under:  8.5 runs
BetMGM:  Moneyline odds:  Mariners -150, Angels +125; Over/Under:  8.5 runs

Season Record

Seattle Mariners:  55-48 (2nd place, AL West)
Los Angeles Angels:  49-54 (4th place, AL West)

Do not miss out on our expert handicapper analysis! Matt Fargo is on a HOT STREAK in the MLB on a 36-34 MLB RUN for +$12,430 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.


Recent Form
Seattle Mariners:  7-3 last 10
Los Angeles Angels:  4-6 last 10



Seattle Mariners vs Los Angeles Angels Preview and Analysis


The Mariners are entering this series off a loss and lost their 3-game series against the Milwaukee Brewers 2-1 in their last series. They enter this game with a 55-48 record overall and have a road record of 27-24. This is the 3rd game of a 4-game series with the Angels on Saturday with the 2nd game of this series still to be played on Friday. The Mariners won the series opener on Thursday. Their offense ranks 8th in the MLB with a .735 OPS. Bryan Woo is their starting pitcher on Friday while George Kirby is making his start in this game on Saturday. He is 4-5 with a 4.65 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 ER, 0 HR, and 1 BB with 3 SO on 5 hits through 6 IP against the Milwaukee Brewers.

The Angels are entering this series off a loss and got swept in their 3-game series against the New York Mets 3-0 in their last series. They enter this game with a 49-54 record overall and have a home record of 24-24. This is the 3rd game of a 4-game series with the Mariners on Saturday with the 2nd game of this series still to be played on Friday. The Angels lost the 1st game of this series on Thursday. Their offense ranks 15th in the MLB with a .716 OPS. José Soriano is their starting pitcher on Friday while Tyler Anderson is making his start in this game on Saturday. He is 2-6 with a 4.43 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 4 earned runs, 1 homer, and 5 walks with 4 strikeouts on 4 hits through 6 innings pitched against the New York Mets.


Mariners vs Angels Prediction

The current betting odds have the Mariners listed as a favorite in this game according to Draftkings Sportsbook. The Mariners have looked good in their games this season with their 55-48 record overall which has them right near the top of the AL West. They have also been a good road team this year with their 27-24 road record. Meanwhile, the Angels haven't looked great in their games this season with their 49-54 record overall which has them right near the bottom of the AL West. They have looked better in their own ballpark though with their 24-24 home record this season. Neither team has a solid starter going in this one, but the Mariners do have the better offense and they have been the hotter team lately, going 7-3 in their last 10 games while the Angels are 4-6. The Mariners are going with Kirby in this one and he hasn't looked great this season. He is 4-5 with a 4.65 ERA and has been giving up some runs this season. He gave up another 4 earned runs in his last start too, but the team has still been having success with him lately as they have won 3 of the last 4 games he started in. The Angels are going with Anderson in this one and he hasn't looked great this season either. He is 2-6 with a 4.43 ERA and his team hasn't been having a ton of success with him lately. He gave up another 4 earned runs in his last start and the team has lost 2 of the last 3 games he started in too. The Mariners already took the 1st game of this series on Thursday and they have the momentum on their side right now. The best way to place a bet here is on the Mariners to win this game. 

Mariners Angels Prediction:  Our MLB Pick for Saturday, July 26, 2025 (9:38 pm ET start time) is Mariners 8 Angels 4.
Don't miss our champion handicappers free picks, best bets, and expert baseball picks today.  And if you enjoyed this Seattle Mariners Los Angeles Angels prediction, be sure to drop by every day for our daily MLB projections and previews.

MLB Betting Trends


Seattle Mariners: 95-63 (+8.2 units) on the moneyline vs. AL teams scoring 4.4 or less runs/game on the season. 84-51 (+18.9 units) on the moneyline against division opponents. 148-109 (+15.5 units) on the moneyline vs. an AL team with an on base percentage .330 or worse. 44-22 OVER on the road vs. good power teams - averaging 1.25 or more HR's/game.

Los Angeles Angels: 185-242 (-27.7 units) on the moneyline in all games. 94-116 (-27.1 units) on the moneyline in home games. 146-186 (-13.7 units) on the moneyline against right-handed starters. 71-50 OVER against division opponents.

Key Injuries


Seattle Mariners:  B. Miller (SP) Fifteen Day IL - Elbow. C. Snider (RP) Fifteen Day IL - Forearm. G. Santos (RP) Sixty Day IL - Knee. V. Robles (RF) Sixty Day IL - Shoulder. R. Bliss (2B) Sixty Day IL - Biceps.

Los Angeles Angels:  J. Soler (RF) Day To Day - Back. H. Strickland (RP) Sixty Day IL - Shoulder. C. Moore (2B) Ten Day IL - Thumb. R. Stephenson (RP) Sixty Day IL - Bicep. B. Joyce (RP) Sixty Day IL - Shoulder. A. Rendon (3B) Sixty Day IL - Hip.


Notable Quotes


“This is a good position where we’ve been able to get ourselves into a good spot here in the standings. It’s time to go. We get down to the last 59 games here, and we’re excited about where we’re at. There’s a lot of exciting times -- a lot of fun times -- ahead of us, and we’re looking forward to that.” - Dan Wilson after his team’s win against the LA Angels in their game on Thursday.


"[The calls] were bad. I went out and I didn’t say anything really [about the calls]. I said, ‘You have to keep them on the plate.’ Before I could tell him that [Lamonte] Wade [Jr.] was going into right field, he threw me out, which is what really got me going -- aside from the obvious missed calls.” - Ray Montgomery after his team’s loss against the Mets in their game on Wednesday.


Starting Lineups


Seattle Mariners
J.P. Crawford (L) SS
Julio Rodríguez (R) CF
Cal Raleigh (S) C
Randy Arozarena (R) LF
Mitch Garver (R) DH
Jorge Polanco (S) 2B
Donovan Solano (R) 1B
Dylan Moore (R) RF
Ben Williamson (R) 3B

Los Angeles Angels
Zach Neto (R) SS
Mike Trout (R) DH
Nolan Schanuel (L) 1B
Taylor Ward (R) LF
Yoán Moncada (S) 3B
Jo Adell (R) CF
Travis d'Arnaud (R) C
LaMonte Wade Jr. (L) RF
Luis Rengifo (S) 2B

Statistical Leaders


Seattle Mariners
Batting Average:  Dominic Canzone (.300)
Hits:  Julio Rodríguez (107)
Home Runs:  Cal Raleigh (39)
RBI:  Cal Raleigh (84)
Stolen Bases:  Julio Rodríguez (20)
Wins:  Bryan Woo (8)
Saves:  Andrés Muñoz (23)
ERA:  Sauryn Lao (0.00)

Los Angeles Angels
Batting Average:  Nolan Schanuel (.276)
Hits:  Nolan Schanuel (102)
Home Runs:  Taylor Ward (23)
RBI:  Taylor Ward (76)
Stolen Bases:  Zach Neto (18)
Wins:  José Soriano (7)
Saves:  Kenley Jansen (17)
ERA:  Robert Stephenson (0.00)

Managers:
Seattle Mariners: Dan Wilson (2nd season)
Los Angeles Angels: Ray Montgomery (Interim)


Rod Pearson

About the Author:

Rod Pearson has been a rabid sports fan his entire life.  He grew up in Ontario, and was skilled in both hockey and baseball, and pitched in an elite baseball league for many years.  In 2022, Rod decided to hang up his glove, so that he could write about the sports he loves -- but from a gambling perspective.  Join Rod every day as he breaks down the games to find the best betting value.

All photographic images used for editorial content have been licensed from the Associated Press.

© 2025 Al McMordie's BigAl.com. All Rights Reserved.