New York Yankees vs Toronto Blue Jays Prediction, Preview and Odds - 07/23/2025

Game Time: 7:07 pm ET, Wednesday, July 23, 2025

Venue:  Rogers Centre, Toronto, ON

Where to Watch:  Prime Video

DraftKings:  Moneyline odds:  Yankees -137, Blue Jays +112; Over/Under:  8 runs

Bet365:  Moneyline odds:  Yankees -140, Blue Jays +115; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Yankees -140, Blue Jays +115; Over/Under:  8 runs

New York Yankees:  55-45 (2nd place, AL East)

Toronto Blue Jays:  59-41 (1st place, AL East)

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New York Yankees:  6-4 last 10

Toronto Blue Jays:  7-3 last 10

The Yankees are entering this series off a win and won their 3-game series against the Atlanta Braves 2-1 in their last series. They enter this game with a 55-45 record overall and have a road record of 25-26. This is the series finale of a 3-game series with the Blue Jays on Wednesday with the 2nd game still to be played on Tuesday. The Yankees lost the series opener on Monday. Their offense ranks 1st in the MLB with a .789 OPS. Rookie pitcher Cam Schlittler is their starting pitcher on Tuesday while Max Fried is making his start in this game on Wednesday. He is 11-3 with a 2.43 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 3 ER, 0 HR, and 3 BB with 2 SO on 6 hits through 3 IP against the Chicago Cubs.

The Blue Jays are entering this series off a win and completed the sweep in their 3-game series against the San Francisco Giants 3-0 in their last series. They enter this game with a 59-41 record overall and have a home record of 36-16. This is the 3rd game of a 3-game series with the Yankees on Wednesday with the 2nd game of this series still to be played on Tuesday. The Blue Jays won the 1st game of this series on Monday. Their offense ranks 6th in the MLB with a .740 OPS. Max Scherzer is their starting pitcher on Tuesday while Chris Bassitt is making his start in this game on Wednesday. He is 10-4 with a 3.89 ERA this season. His team won 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 earned runs, 0 homers, and 0 walks with 5 strikeouts on 10 hits through 6.1 innings pitched against the San Francisco Giants.

The current betting odds have the Blue Jays listed as an underdog in this game according to Draftkings Sportsbook. The Blue Jays have looked great in their games this season with their 59-41 record overall which has them right at the top of the AL East. They have looked great in their own ballpark too with their 36-16 home record this season. Meanwhile, the Yankees have looked really good in their games this season with their 55-45 record overall which has them right near the top of the AL East. They haven't been a good road team though with their 25-26 road record this season. The Yankees have also been in a big slump lately. They are starting to pull themselves out of it as they are now 6-4 in their last 10 games, but the Blue Jays are still 7-3 in their last 10 games and have been red hot. They are also going to have a solid starter on the mound here with Bassitt starting in this one. He is 10-4 with a 3.89 ERA and hasn't been giving up many runs lately. He is coming off another great start in which he gave up no runs and his team has won 3 of their last 4 games with him starting too. The Yankees are going with Fried in this one and he has also looked great this season. He is 11-3 with a 2.43 ERA, but lately he has been giving up more runs in his starts. He is coming off a start in which he gave up 3 earned runs, something that has become a common theme for him in his last few starts, and even the team has lost 2 of their last 3 games with him starting. The Blue Jays are rolling right now, already taking the 1st game of this series, and they will be looking to stay ahead in the AL East with another series win here. The best way to place a bet here is on the Blue Jays to win this game. 

Yankees Blue Jays Prediction:  Our MLB Pick for Wednesday, July 23, 2025 (7:07 pm ET start time) is Blue Jays 3 Yankees 1.

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New York Yankees: 117-73 (+9.1 units) on the moneyline vs. an AL team with a slugging percentage .410 or worse on the season. 126-107 (+5.9 units) on the moneyline when playing against a team with a winning record. 8-5 (+3.3 units) on the moneyline vs. a starting pitcher whose winning percentage is better than 70%. 18-9 OVER as a road favorite of -125 to -175.

Toronto Blue Jays: 222-204 (-11.7 units) on the moneyline in all games. 118-96 (-9.1 units) on the moneyline in home games. 60-75 (-21.2 units) on the moneyline against division opponents. 32-16 OVER vs. an AL team with a slugging percentage of .440 or better on the season.

New York Yankees:  M. Fried (SP) Day To Day - Finger. C. Schmidt (SP) Fifteen Day IL - Forearm. M. Leiter Jr. (RP) Fifteen Day IL - Fibular. F. Cruz (RP) Fifteen Day IL - Oblique. R. Yarbrough (SP) Fifteen Day IL - Oblique. Y. De Los Santos (RP) Fifteen Day IL - Elbow. O. Cabrera (3B) Sixty Day IL - Ankle. J. Cousins (RP) Sixty Day IL - Elbow. L. Gil (SP) Sixty Day IL - Back. G. Cole (SP) Sixty Day IL - Elbow.

Toronto Blue Jays:  R. Burr (RP) Sixty Day IL - Shoulder. N. Sandlin (RP) Fifteen Day IL - Elbow. A. Gimenez (2B) Ten Day IL - Ankle. Y. Garcia (RP) Fifteen Day IL - Ankle. A. Santander (RF) Sixty Day IL - Shoulder. P. Schultz (RP) Fifteen Day IL - Middle Finger. B. Francis (SP) Fifteen Day IL - Shoulder. D. Varsho (CF) Ten Day IL - Hamstring. A. Manoah (SP) Sixty Day IL - Elbow. A. Bastardo (SP) Sixty Day IL - Elbow.

“It’s been a month now where we haven’t been our best. We need to obviously start playing better consistently and putting wins in the win column.” - Aaron Boone after his team’s loss against the Blue Jays in their game on Monday.

“That’s Kev. Pete [Walker] and I were joking before the game that we needed a gem from Kevin. He did it.” - John Schneider after his team’s win against the Yankees in their game on Monday.

Trent Grisham (L) CF

Aaron Judge (R) RF

Jazz Chisholm Jr. (L) 2B

Giancarlo Stanton (R) DH

Jasson Domínguez (S) LF

Paul Goldschmidt (R) 1B

Austin Wells (L) C

Anthony Volpe (R) SS

Oswald Peraza (R) 3B

Ernie Clement (R) 3B

George Springer (R) DH

Vladimir Guerrero Jr. (R) 1B

Bo Bichette (R) SS

Alejandro Kirk (R) C

Davis Schneider (R) LF

Myles Straw (R) CF

Leo Jiménez (R) 2B

Joey Loperfido (L) RF

Batting Average:  Aaron Judge (.349)

Hits:  Aaron Judge (128)

Home Runs:  Aaron Judge (36)

RBI:  Aaron Judge (82)

Stolen Bases:  Jasson Domínguez (14)

Wins:  Max Fried (11)

Saves:  Devin Williams (14)

ERA:  Adam Ottavino (0.00)

Batting Average:  Tyler Heineman (.341)

Hits:  Bo Bichette (115)

Home Runs:  George Springer (17)

RBI:  Bo Bichette (57)

Stolen Bases:  George Springer (12)

Wins:  Chris Bassitt (10)

Saves:  Jeff Hoffman (24)

ERA:  Ryan Burr (0.00)

Managers:

New York Yankees: Aaron Boone (8th season)

Toronto Blue Jays: John Schneider (4th season)