New York Mets vs San Francisco Giants Prediction, Preview and Odds - 07/26/2025

Game Time: 9:05 pm ET, Saturday, July 26, 2025

Venue:  Oracle Park, San Francisco, CA

Where to Watch:  SNY, NBCS-BA, KNTV

DraftKings:  Moneyline odds:  Mets -101, Giants -121; Over/Under:  7.5 runs

Bet365:  Moneyline odds:  Mets +100, Giants -120; Over/Under:  7.5 runs

BetMGM:  Moneyline odds:  Mets +100, Giants -120; Over/Under:  7.5 runs

New York Mets:  59-44 (1st place, NL East)

San Francisco Giants:  54-49 (3rd place, NL West)

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New York Mets:  6-4 last 10

San Francisco Giants:  3-7 last 10

The Mets are entering this series off a win and completed the sweep in their 3-game series against the Los Angeles Angels 3-0 in their last series. They enter this game with a 59-44 record overall and have a road record of 22-28. This is the 2nd game of a 3-game series with the Giants on Saturday with the series opener still to be played on Friday. Their offense ranks 10th in the MLB with a .733 OPS. Clay Holmes is their starting pitcher on Friday while David Peterson is making his start in this game on Saturday. He is 6-4 with a 2.90 ERA this season. His team won 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 0 ER, 0 HR, and 1 BB with 4 SO on 4 hits through 6 IP against the Cincinnati Reds.

The Giants are entering this series off a win and won their 3-game series against the Atlanta Braves 2-1 in their last series. They enter this game with a 54-49 record overall and have a home record of 28-20. This is the 2nd game of a 3-game series with the Mets on Saturday with the 1st game of this series still to be played on Friday. Their offense ranks 24th in the MLB with a .687 OPS. Logan Webb is their starting pitcher on Friday while Robbie Ray is making his start in this game on Saturday. He is 9-4 with a 2.92 ERA this season. His team lost their last 2 straight games this season with him making an appearance. In his last MLB regular season start, he allowed 5 earned runs, 2 homers, and 5 walks with 3 strikeouts on 5 hits through 4.1 innings pitched against the Toronto Blue Jays.

The current betting odds have the Giants listed as a slight favorite in this game according to Draftkings Sportsbook. The Giants have looked good in their games this season with their 54-49 record overall which has them right in the middle of the NL West. They have also looked a lot better in their own ballpark this year with their 28-20 home record. Meanwhile, the Mets have looked great in their games this season with their 59-44 record overall which has them right at the top of the NL East. They haven't been a good road team though with their 22-28 road record this season. The Mets have been the hotter team lately as they are 6-4 in their last 10 games while the Giants are only 3-7, but the Giants do have the better pitching matchup here and can take advantage of that at home. The Giants are going with Ray in this one and he has been one of their best starters all season. He is 9-4 with a 2.92 ERA and hasn't been giving up many runs lately. The team has lost 2 games in a row now with him starting and he did give up 5 earned runs in his last start, but that hasn't been a common theme for him this year and he will be looking to bounce back at home. The Mets are going with Peterson in this one and he has also looked good this season. He is 6-4 with a 2.90 ERA and hasn't been giving up many runs lately either. He is coming off a great start in which he gave up no runs and the team has won 2 of their last 3 games with him starting too, but he hasn't been as good in his road starts so this is a good opportunity for the Giants to get a much needed bounce back win. The best way to place a bet here is on the Giants to win this game. 

Mets Giants Prediction:  Our MLB Pick for Saturday, July 26, 2025 (9:05 pm ET start time) is Giants 2 Mets 0.

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New York Mets: 230-210 (-10 units) on the moneyline in all games. 101-119 (-21.2 units) on the moneyline in road games. 63-99 (-19.8 units) on the moneyline as an underdog of +100 or higher. 13-6 UNDER against NL West opponents.

San Francisco Giants: 49-39 (+8.2 units) on the moneyline at home when the money line is +125 to -125. 50-47 (+9.9 units) on the moneyline vs. an NL starting pitcher whose WHIP is 1.250 or better. 55-51 (+9.9 units) on the moneyline when playing against a good team (Win Pct. 54% to 62%). 85-52 UNDER as a home favorite of -110 or higher.

New York Mets:  B. Waddell (RP) Fifteen Day IL - Hip. D. Nunez (RP) Sixty Day IL - Elbow. J. Winker (LF) Ten Day IL - Back. T. Megill (SP) Sixty Day IL - Elbow. P. Blackburn (SP) Fifteen Day IL - Shoulder. G. Canning (SP) Sixty Day IL - Achilles. J. Siri (CF) Sixty Day IL - Shin. M. Kranick (RP) Fifteen Day IL - Elbow. D. Young (RP) Sixty Day IL - Elbow. A. Minter (RP) Sixty Day IL - Lat. C. Scott (SP) Sixty Day IL - Elbow. N. Madrigal (3B) Sixty Day IL - Shoulder. D. Smith (RP) Sixty Day IL - Elbow.

San Francisco Giants:  E. Miller (RP) Fifteen Day IL - Elbow. C. Koss (2B) Ten Day IL - Hamstring. J. Encarnacion (RF) Ten Day IL - Oblique. T. Murphy (C) Sixty Day IL - Back.

“We’re going to need those guys. We know that they’re going through it. But they’re too good, man. They’re too good of hitters. They’re too good of players. And I’m glad that they were able to come through for us today.” - Carlos Mendoza after his team’s win against the LA Angels in their game on Wednesday.

“We know every time he goes out there guys try extra hard and for whatever reason it just hasn’t worked out. For him to be able to get through five after throwing [40] pitches in the first inning, there’s some toughness involved in that. [There’s] a lot of heat out there. He knows that bullpen-wise we’re beat up, too. To get through the first was huge for him.” - Bob Melvin after his team’s win against the Braves in their game on Wednesday.

Brandon Nimmo (L) LF

Francisco Lindor (S) SS

Juan Soto (L) RF

Pete Alonso (R) 1B

Starling Marte (R) DH

Brett Baty (L) 2B

Mark Vientos (R) 3B

Luis Torrens (R) C

Tyrone Taylor (R) CF

Heliot Ramos (R) LF

Rafael Devers (L) DH

Willy Adames (R) SS

Matt Chapman (R) 3B

Mike Yastrzemski (L) RF

Casey Schmitt (R) 2B

Dominic Smith (L) 1B

Patrick Bailey (S) C

Luis Matos (R) CF

Batting Average:  José Azocar (.278)

Hits:  Pete Alonso (104)

Home Runs:  Juan Soto (24)

RBI:  Pete Alonso (80)

Stolen Bases:  Francisco Lindor (16)

Wins:  Clay Holmes (8)

Saves:  Edwin Díaz (21)

ERA:  Rico Garcia (0.00)

Batting Average:  Heliot Ramos (.267)

Hits:  Heliot Ramos (104)

Home Runs:  Willy Adames (15)

RBI:  Wilmer Flores (59)

Stolen Bases:  Tyler Fitzgerald (9)

Wins:  Robbie Ray (9)

Saves:  Camilo Doval (15)

ERA:  Matt Gage (0.00)

Managers:

New York Mets: Carlos Mendoza (2nd season)

San Francisco Giants: Bob Melvin (2nd season)