Milwaukee Bucks vs Indiana Pacers Prediction, Preview and Odds - 04/22/2025

Game Time: 7:00 pm ET, Tuesday, April 22, 2025

Venue:  Gainbridge Fieldhouse, Indianapolis, IN

Where to Watch:  NBA TV

DraftKings:  Point Spread:  Bucks +4.5, Pacers -4.5; Over/Under:  227.5 points

Bet365:  Point Spread:  Bucks +4.5, Pacers -4.5; Over/Under:  227.5 points

BetMGM:  Point Spread:  Bucks +4.5, Pacers -4.5; Over/Under:  227.5 points

Milwaukee Bucks:  48-34 (3rd place, Central Division)

Indiana Pacers:  50-32 (2nd place, Central Division)

Do not miss out on our expert handicapper analysis! Jim Feist is on a HOT STREAK in the NBA on a 25-8 NBA RUN for +$16,150 PROFIT! Make sure you check out his picks and many more from the expert handicappers featured in the Shop Picks section.

Milwaukee Bucks:  8-2 last 10

Indiana Pacers:  8-2 last 10

The Bucks are entering the playoffs with a 48-34 record overall this season and they were 20-20 in their road games where they will be in this game. They are entering this game off a loss against the Indiana Pacers. Giannis Antetokounmpo led the team in points in that game with 36 while AJ Green was next on the team with 15 points. Kevin Porter Jr. led the team in assists in that game with 5 while Giannis Antetokounmpo led the team in rebounds with 12. They were 41.7% from the field, 24.3% from 3-point range, and 67.9% from the free throw line with their shots in that game. Their offense is averaging 115.5 PPG and their defense is allowing their opponents to average 113 PPG against them. The Bucks have an ATS record of 43-39-2 this season and their O/U record is 43-41.

The Pacers are entering the playoffs with a 50-32 record overall this season and they were 29-11 in their home games where they will be in this game. They are entering this game on a 2 game winning streak with wins coming against the Cleveland Cavaliers and the Milwaukee Bucks. Pascal Siakam led the team in points in that game with 25 while Myles Turner was next on the team with 19 points. Tyrese Haliburton led the team in assists in that game with 12 while Pascal Siakam and Tyrese Haliburton each led the team in rebounds with 7. They were 51.9% from the field, 38.2% from 3-point range, and 76.9% from the free throw line with their shots in that game. Their offense is averaging 117.4 PPG and their defense is allowing their opponents to average 115.1 PPG against them. The Pacers have an ATS record of 37-43-3 this season and their O/U record is 43-38-2.

The current betting odds have the Pacers listed as a 4.5 point favorite in this game according to Draftkings Sportsbook. This is game 2 of a 7 game series between the 4th seeded Pacers and the 5th seeded Bucks from the Eastern Conference for the 1st round of the NBA playoffs. The Pacers are leading this series 1-0 after game 1. The Pacers took a 1-0 series lead after beating the Bucks at home 117-98. The Bucks were able to hang around in that game for the 1st quarter, but it was over shortly after as the Pacers took a double digit lead in the 2nd quarter and never really looked back. The Pacers were a lot better on their home court this season and they were really hot to end the regular season too. They have continued that into this series and really took advantage of a banged up Bucks team that is still missing Lillard. Lillard is supposed to come back for this series, but it likely won't be in the next game and that is going to be a big blow to the Bucks since Giannis looked like he was out there by himself in game 1. The Pacers have too much talent for Giannis to carry this team on his own, especially on the road, so the Bucks aren't going to be a real threat until they get back home and until Lillard has a chance to come back. The Bucks were very good against the Pacers this season, but this is still the same Pacers team that dominated the Bucks last year and even kicked them out of the playoffs. They know what they need to do to beat a team like the Bucks in the playoffs so look for them to take advantage of the Bucks again here. The best way to place a bet here is on the Pacers to cover the spread in this game. 

Bucks Pacers Prediction:  Our NBA Pick for Tuesday, April 22, 2025 (7:00 pm ET start time) is Pacers 131 Bucks 114.

Don't miss our champion handicappers free picks and expert basketball picks today.  And if you enjoyed this Milwaukee Bucks Indiana Pacers prediction, be sure to drop by every day for our weekly NBA predictions and previews.

Milwaukee Bucks: 11-23 ATS as a road underdog of 6 points or less. 4-8 ATS in the first round of the playoffs. 15-25 ATS when playing against a good team (Win Pct. 60% to 70%). 9-3 OVER in the first round of the playoffs. 5-1 OVER when trailing in a playoff series. 24-16 OVER when playing against a good team (Win Pct. 60% to 70%).

Indiana Pacers: 23-15 ATS as a home favorite of 6 points or less. 87-54 ATS versus good 3 point shooting teams - making 36% of their attempts or more. 41-21 ATS when playing only their 2nd game in 5 days. 23-16 OVER as a home favorite of 6 points or less. 3-0 OVER in the 2nd game of a playoff series.

Milwaukee Bucks:  T. Smith (PF) Day To Day - Ankle. D. Lillard (PG) Day To Day - Calf.

Indiana Pacers:  Q. Jackson (PG) Out For Season - Calf.

“I think we were late, like we got into scrambling mode and they would create for the next guy and that's what they want you to do. We didn't have enough urgency. Going into Game 2, hopefully we can change that.” - Giannis Antetokounmpo after their loss against the Pacers in game 1 of this series.

“The series is one-seventh over, and Game 2 will be monumentally more difficult than this one. Everybody on our team has got to be armed and dangerous. Striking the right balance is everything for our team.” - Rick Carlisle after his team’s win against the Bucks in game 1 of this series.

PG Kevin Porter Jr.

SG Taurean Prince

SF Kyle Kuzma

PF Giannis Antetokounmpo

C Brook Lopez

PG Tyrese Haliburton

SG Andrew Nembhard

SF Aaron Nesmith

PF Pascal Siakam

C Myles Turner

PPG: G. Antetokounmpo (30.4)

APG: D. Lillard (7.1)

Reb/G: G. Antetokounmpo (11.9)

PPG: P. Siakam (20.2)

APG: T. Haliburton (9.2)

Reb/G: P. Siakam (6.9)

Coaches:

Milwaukee Bucks: Doc Rivers (2nd season)

Indiana Pacers: Rick Carlisle (4th season)