Memphis Grizzlies vs Oklahoma City Thunder Prediction, Preview and Odds - 04/22/2025

Game Time: 7:30 pm ET, Tuesday, April 22, 2025

Venue:  Paycom Center, Oklahoma City, OK 

Where to Watch:  TNT, MAX, truTV

DraftKings:  Point Spread:  Grizzlies +15, Thunder -15; Over/Under:  229 points

Bet365:  Point Spread:  Grizzlies +15, Thunder -15; Over/Under:  229 points

BetMGM:  Point Spread:  Grizzlies +14.5, Thunder -14.5; Over/Under:  228.5 points

Memphis Grizzlies:  48-34 (2nd place, Southwest Division)

Oklahoma City Thunder:  68-14 (1st place, Northwest Division)

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Memphis Grizzlies:  5-5 last 10

Oklahoma City Thunder:  8-2 last 10

The Grizzlies are entering the playoffs with a 48-34 record overall this season and they were 22-19 in their road games where they will be in this game. They are entering this game off a loss against the Oklahoma City Thunder. Ja Morant and Marvin Bagley III each led the team in points in that game with 17 while Desmond Bane was next on the team with 9 points. Scotty Pippen Jr. and Ja Morant each led the team in assists in that game with 4 while Zach Edey led the team in rebounds with 9. They were 34.4% from the field, 17.6% from 3-point range, and 83.3% from the free throw line with their shots in that game. Their offense is averaging 121.7 PPG and their defense is allowing their opponents to average 116.9 PPG against them. The Grizzlies have an ATS record of 43-41-1 this season and their O/U record is 48-37.

The Thunder are entering the playoffs with a 68-14 record overall this season and they were 35-6 in their home games where they will be in this game. They are entering this game on a 5 game winning streak with wins coming against the Los Angeles Lakers, the Phoenix Suns, the Utah Jazz, the New Orleans Pelicans, and the Memphis Grizzlies. Aaron Wiggins led the team in points in that game with 21 while Jalen Williams was next on the team with 20 points. Jalen Williams led the team in assists in that game with 6 while Chet Holmgren led the team in rebounds with 10. They were 50.5% from the field, 35.4% from 3-point range, and 93.3% from the free throw line with their shots in that game. Their offense is averaging 120.5 PPG and their defense is allowing their opponents to average 107.6 PPG against them. The Thunder have an ATS record of 54-26-4 this season and their O/U record is 45-37-2.

The current betting odds have the Thunder listed as a 15 point favorite in this game according to Draftkings Sportsbook. This is game 2 of a 7 game series between the 1st seeded Thunder and the 8th seeded Grizzlies from the Western Conference for the 1st round of the NBA playoffs. The Thunder are leading the series 1-0 after game 1. The Thunder looked really good in game 1 of this series as they won 131-80. That game was over very early as the Thunder took a double digit lead in the 1st quarter and never really looked back. The Thunder have had a lot more rest for this series since the Grizzlies had to play in the play-in tournament, but the Thunder have also been beating up on the Grizzlies all year. Their last meeting in the regular season ended 125-104 for the Thunder and the Thunder have won all of their games against the Grizzlies this season by double digits. It doesn't help the Grizzlies that their best player Ja Morant picked up an injury in the play-in tournament and isn't fully healthy now as he deals with that injury. The Thunder were the best team in the NBA this season with their record in the regular season and they also have one of the best home records too. Their playoff run ended in disappointment last year, but they have that experience to draw on now and can take advantage of the Grizzlies here with their best player banged up. Look for the Thunder to come out really strong again in this game and take a 2-0 series lead as none of the games these two have played against each other all season have even been close. The best way to place a bet here is on the Thunder to cover the spread in this game. 

Grizzlies Thunder Prediction:  Our NBA Pick for Tuesday, April 22, 2025 (7:30 pm ET start time) is Thunder 136 Grizzlies 111.

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Memphis Grizzlies: 16-37 ATS against Northwest division opponents. 3-6 ATS as a road underdog of 12.5 or more points. 9-18 ATS revenging a blowout loss vs opponent of 20 points or more. 19-8 OVER revenging a blowout loss vs opponent of 20 points or more. 

Oklahoma City Thunder: 17-5 ATS as a home favorite of 12.5 to 18 points. 28-18 ATS after a blowout win by 20 points or more. 33-18 ATS after allowing 100 points or less. 77-49 OVER after playing a home game.

Memphis Grizzlies:  G. Jackson (PF) Day To Day - Personal. J. Wells (SG) Out For Season - Wrist. B. Clarke (PF) Out For Season - Knee.

Oklahoma City Thunder:  O. Dieng (C) Day To Day - Calf. N. Topic (PG) Out For Season - ACL.

“If you’re in a playoff series, it’s a best of seven. It doesn’t matter if you win by one point on a buzzer-beater or you win by 50 points, you get one win. So luckily for us, there’s only one way from this and that’s up. And we will analyze it and learn from it. And then we will fix those things that hurt us.” - Tuomas Iisalo after his team’s loss against the OKC Thunder in game 1 of this series on Sunday.

“They played 36 hours ago and had an emotional game, had to turn around and play at noon today, which is a really tough turnaround. So they’re going to be better Tuesday. So I thought we did a good job. But I don’t think we can expect that from them (again). You know they’re going to play a lot better than that.” - Mark Daigneault after his team’s win against the Grizzlies in game 1 of this series on Sunday.

PG Ja Morant

SG Desmond Bane

SF Vince Williams Jr.

PF Jaren Jackson Jr.

C Zach Edey 

PG Shai Gilgeous-Alexander

SG Luguentz Dort

SF Jalen Williams

PF Chet Holmgren

C Isaiah Hartenstein

PPG: J. Morant (23.2)

APG: J. Morant (7.3)

Reb/G: Z. Edey (8.3)

PPG: S. Gilgeous-Alexander (32.7)

APG: S. Gilgeous-Alexander (6.4)

Reb/G: I. Hartenstein (10.7)

Coaches:

Memphis Grizzlies: Tuomas Iisalo (Interim)

Oklahoma City Thunder: Mark Daigneault (5th season)