Cleveland Guardians vs New York Mets Prediction, Preview and Odds - 08/05/2025

Game Time: 7:10 pm ET, Tuesday, August 5, 2025

Venue:  Citi Field, Flushing, NY 

Where to Watch:  CLEGUARDIANS.tv, SNY

DraftKings:  Moneyline odds:  Guardians +162, Mets -200; Over/Under:  8 runs

Bet365:  Moneyline odds:  Guardians +160, Mets -200; Over/Under:  8 runs

BetMGM:  Moneyline odds:  Guardians +160, Mets -200; Over/Under:  8 runs

Cleveland Guardians:  56-55 (2nd place, AL Central)

New York Mets:  63-49 (2nd place, NL East)

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Cleveland Guardians:  5-5 last 10

New York Mets:  5-5 last 10

The Guardians are entering this series off a loss and won their 3-game series against the Minnesota Twins 2-1 in their last series. They enter this game with a 56-55 record overall and have a road record of 27-28. This is the 2nd game of a 3-game series with the Mets on Tuesday with the series opener still to be played on Monday. Their offense ranks 27th in the MLB with a .680 OPS. Slade Cecconi is their starting pitcher on Monday while Logan Allen is making his start in this game on Tuesday. He is 7-9 with a 4.06 ERA this season. His team lost 2 of their last 3 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 ER, 2 HR, and 1 BB with 3 SO on 8 hits through 7 IP against the Colorado Rockies.

The Mets are entering this series off a loss and lost their 3-game series against the San Francisco Giants 2-1 in their last series. They enter this game with a 63-49 record overall and have a home record of 38-18. This is the 2nd game of a 3-game series with the Guardians on Tuesday with the 1st game of this series still to be played on Monday. Their offense ranks 11th in the MLB with a .728 OPS. Sean Manaea is their starting pitcher on Monday while Clay Holmes is making his start in this game on Tuesday. He is 9-6 with a 3.45 ERA this season. His team lost 3 of their last 4 games this season with him making an appearance. In his last MLB regular season start, he allowed 2 earned runs, 1 homer, and 2 walks with 3 strikeouts on 8 hits through 3.2 innings pitched against the San Diego Padres.

The current betting odds have the Mets listed as a big favorite in this game according to Draftkings Sportsbook. The Mets have looked really good in their games this season with their 63-49 record overall which has them right near the top of the NL East. They have also looked great in their own ballpark this year with their 38-18 home record, one of the best home records in the entire MLB. Meanwhile, the Guardians have looked good in their games this season with their 56-55 record overall which has them right near the top of the AL Central. They haven't been a great road team though with their 27-28 road record. The Guardians haven't been that consistent though as they have struggled to stay above .500 this season and the Mets can take advantage of that at home with the better pitching matchup here. Holmes is on the mound for the Mets in this one and he has looked good this season. He is 9-6 with a 3.45 ERA and hasn't been giving up many runs lately. The team has struggled lately, losing 3 of their last 4 games with him starting, but he only gave up 2 earned runs in his last start and the Mets have the stronger offense to help out too. The Guardians are going with Allen in this one and he hasn't looked bad this season. He is 7-9 with a 4.09 ERA and has been giving up some runs in his starts this year. He also gave up 2 earned runs in his last start, but that hasn't been a common theme for him this year and the team has also struggled with him lately, losing 2 of the last 3 games he started in. The Mets haven't looked great lately, but their offense has been a lot more consistent this season and they have the edge at home with this pitching matchup. The best way to place a bet here is on the Mets to win this game, and on the runline. 

Guardians Mets Prediction:  Our MLB Pick for Tuesday, August 5, 2025 (7:10 pm ET start time) is Mets 5 Royals 2.

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Cleveland Guardians: 104-118 (-8.5 units) on the moneyline in road games. 85-120 (-13 units) on the moneyline as an underdog of +100 or higher. 58-70 (-17.9 units) on the moneyline in an inter-league game. 27-15 UNDER as a road underdog of +150 or more.

New York Mets: 130-93 (+9.2 units) on the moneyline in home games. 101-63 (+6.8 units) on the moneyline as a home favorite of -110 or higher. 148-128 (+6.2 units) on the moneyline in night games. 27-18 UNDER as a favorite of -175 to -250.

Cleveland Guardians:  L. Thomas (CF) Ten Day IL - Foot. W. Brennan (RF) Sixty Day IL - Forearm. A. Walters (RP) Sixty Day IL - Lat. B. Lively (SP) Sixty Day IL - Forearm. J. Means (SP) Sixty Day IL - Elbow. S. Hentges (RP) Sixty Day IL - Shoulder.

New York Mets:  J. Winker (LF) Sixty Day IL - Back. M. Kranick (RP) Sixty Day IL - Elbow. B. Waddell (RP) Fifteen Day IL - Hip. D. Nunez (RP) Sixty Day IL - Elbow. T. Megill (SP) Sixty Day IL - Elbow. P. Blackburn (SP) Fifteen Day IL - Shoulder. G. Canning (SP) Sixty Day IL - Achilles. J. Siri (CF) Sixty Day IL - Shin. D. Young (RP) Sixty Day IL - Elbow. A. Minter (RP) Sixty Day IL - Lat. C. Scott (SP) Sixty Day IL - Elbow. N. Madrigal (3B) Sixty Day IL - Shoulder. D. Smith (RP) Sixty Day IL - Elbow.

“I just tried to control what's controllable, honestly. I would have liked for [my first hit] to have come a little sooner, maybe an at-bat or two before. But the guys around me make me feel at home. So they made it a lot easier.” - C.J. Kayfus after their loss against the Twins in their game on Sunday.

“What I want to be remembered as is a player of substance. I just want to be remembered as a guy who plays the game hard, the guy who’s, like, the ultimate competitor. I want to be known as a guy that performs and plays the game and wins. That’s really it.” - Pete Alonso after their loss against the Giants in their game on Sunday.

Steven Kwan (L) LF

Daniel Schneemann (L) 2B

José Ramírez (S) 3B

Kyle Manzardo (L) 1B

Bo Naylor (L) C

Gabriel Arias (R) SS

Nolan Jones (L) RF

C.J. Kayfus (L) DH

Angel Martínez (S) CF

Brandon Nimmo (L) LF

Francisco Lindor (S) SS

Juan Soto (L) RF

Pete Alonso (R) 1B

Starling Marte (R) DH

Jeff McNeil (L) 2B

Mark Vientos (R) 3B

Cedric Mullins (L) CF

Francisco Alvarez (R) C

Batting Average:  José Ramírez (.302)

Hits:  José Ramírez (123)

Home Runs:  José Ramírez (23)

RBI:  José Ramírez (61)

Stolen Bases:  José Ramírez (32)

Wins:  Logan Allen (7)

Saves:  Emmanuel Clase (24)

ERA:  Carlos Hernández (0.00)

Batting Average:  José Azocar (.278)

Hits:  Francisco Lindor (112)

Home Runs:  Juan Soto (25)

RBI:  Pete Alonso (86)

Stolen Bases:  Francisco Lindor (17)

Wins:  Clay Holmes (9)

Saves:  Edwin Díaz (23)

ERA:  Brooks Raley (0.00)

Managers:

Cleveland Guardians: Stephen Vogt (2nd season)

New York Mets: Carlos Mendoza (2nd season)